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103,957 results
  • Evidence of distinct gene functional patterns in GC-poor and GC-rich isochores in Bos taurus. [Journal Article]
    Anim Genet 2020Arhondakis S, Milanesi M, … Chillemi G
  • Vertebrate genomes are mosaics of megabase-size DNA segments with a fairly homogeneous base composition, called isochores. They are divided into five families characterized by different guanine-cytosine (GC) levels and linked to several functional and structural properties. The increased availability of fully sequenced genomes allows the investigation of isochores in several species, assessing th…
  • redLips: a comprehensive mechanistic model of the lipid metabolic network of yeast. [Journal Article]
    FEMS Yeast Res 2020Tsouka S, Hatzimanikatis V
  • Over the last decades, yeast has become a key model organism for the study of lipid biochemistry. Because the regulation of lipids has been closely linked to various physiopathologies, the study of these biomolecules could lead to new diagnostics and treatments. Before the field can reach this point, however, sufficient tools for integrating and analyzing the ever-growing availability of lipidomi…
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