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9,659 results
  • Prediction of bioequivalence and food effect using flux and solubility based methods. [Journal Article]
    Mol Pharm 2019Borbas E, K Aacute D Aacute R S, … Pataki H
  • In this paper two different approaches have been developed to predict the food effect and the bioequivalence of marketed itraconazole (ITRA) formulations. The kinetic solubility and simultaneous dissolution-permeation tests of three (ITRA) formulations (Sporanox capsule and solution, and SUBA-ITRA capsule) were carried out in simulated fasted and fed state. Fraction of dose absorbed ratios estima…
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