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1,708 results
  • Anticoagulant Decapeptide Interacts with Thrombin at the Active Site and Exosite-I. [Journal Article]
    J Agric Food Chem 2020; 68(1):176-184Liu H, Tu M, … Du M
  • Thrombin can be used as a target for its inhibitors to prevent blood coagulation. A novel peptide (TKLTEEEKNR, PfCN) identified from αS2-casein (fragments 211-220) with high anticoagulant activity was screened and prepared. The activated partial thromboplastin time, prothrombin time, and thrombin time, at the concentration of 4 mM, prolonged about 19, 2.5 and 5.5 s, respectively. At the same conc…
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