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19,855 results
  • Caveolin-1-derived peptide limits development of pulmonary fibrosis. [Journal Article]
    Sci Transl Med 2019; 11(522)Marudamuthu AS, Bhandary YP, … Shetty S
  • Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with a median 5-year survival of ~20%. Current U.S. Food and Drug Administration-approved pharmacotherapies slow progression of IPF, providing hope that even more effective treatments can be developed. Alveolar epithelial progenitor type II cell (AEC) apoptosis and proliferation, and accumulation of activated myofibroblasts or f…
  • Risks of Genetic Damage in Offspring Conceived Using Sperm Produced during Chemotherapy or Radiotherapy. [Review]
    Andrology 2019Meistrich ML
  • CONCLUSIONS: A schema showing the time from initiation of therapy at which specific antineoplastic agents can cause significant levels of genetic damage in conceptuses and live offspring was developed. The estimates and methods for computing the level of such risk from an individual patient's treatment regimen will enable patients and counselors to make informed decisions on the use of sperm or continuation of a pregnancy.
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