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(bosentan)
2,553 results
  • Recent advances in the workup and management of Raynaud's phenomenon. [Journal Article]
    Pol Arch Intern Med 2019Lis-Święty A
  • Raynaud's phenomenon (RP) is defined as recurrent, reversible episodes of vasospasm involving peripheral small vessels, typically in the fingers and toes. Primary RP (idiopathic RP) is common, occurring in circa 5% of the general population, and is usually benign. Secondary RP accounts for 10-20% of all RP cases and may be associated with complications such as tissue loss, ulcers, and gangrene. S…
  • The effects of bosentan on hyperoxia-induced lung injury in neonatal rats. [Journal Article]
    Pediatr Int 2019Özdemir ÖMA, Taban Ö, … Ergin H
  • Bronchopulmonary dysplasia (BPD) remains to be an important cause of morbidity and mortality in premature infants. Currently, there is no proven effective treatment modality for BPD, and inflammation and oxidative injury play an important role in the pathogenesis of this disease. Herein, the histopathological and biochemical effects of bosentan, which is a non-specific endothelin receptor antagon…
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