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25,785 results
  • Siponimod in the treatment of multiple sclerosis. [Journal Article]
    Expert Opin Investig Drugs 2019Goodman A, Anadani N, Gerwitz L
  • Introduction: Multiple sclerosis (MS) causes focal lesions of immune-mediated demyelinating events followed by slow progressive accumulation of disability. Over the past 2 decades, multiple medications have been studied and approved for use in MS. Most of these agents work by modulating or suppressing the peripheral immune system. Siponimod is a newer-generation sphingosine 1 phosphate (S1P) rece…
  • Management of Calcium Channel Blocker Toxicity in the Pediatric Patient. [Review]
    J Pediatr Pharmacol Ther 2019 Sep-Oct; 24(5):378-389Bartlett JW, Walker PL
  • Calcium channel blockers (CCBs) are commonly prescribed cardiovascular medications used in several disease states including hypertension, coronary artery disease, and atrial fibrillation. Inadvertent exposure or intentional overdose of CCBs may result in hypotension, bradycardia, dysrhythmias, conduction disturbances, and hyperglycemia. In the most severe cases, CCB toxicity can lead to rapid car…
  • Pharmacological evaluation of the hydro-alcoholic extract of Campomanesia phaea fruits in rats. [Journal Article]
    Braz J Biol 2019Wczassek LR, Pontes VCB, Gamberini MT
  • Campomanesia phaea (Myrtaceae), popularly known as cambuci, is one of several species of plants producing comestible fruits, largely used in human nutrition. Despite its consumption and economic potential, limited scientific research is available on the Campomanesia, especially those related to its therapeutic benefits. It is reported by traditional medicine the use of the plant in the treatment …
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