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10,761 results
  • Intravenous N-acetylcysteine in severe cutaneous drug reaction treatment: A case series. [Case Reports]
    SAGE Open Med Case Rep. 2020; 8:2050313X20934708.Hasan MJ, Rabbani R
  • Drug-induced serious adverse reaction is an unpleasant event with high rate of mortality. Stevens-Johnson Syndrome and toxic epidermal necrolysis are most common among the serious adverse drug reactions. There is no selective drug therapy for the management of serious adverse drug reactions-associated mucocutaneous blisters. The use of N-acetylcysteine in the treatment of mucocutaneous blisters h…
  • [Immunomorphology of bullous lesions of the oral mucosa]. [Journal Article]
    Stomatologiia (Mosk). 2020; 99(3):18-21.Rabinovich OF, Babichenko II, Abramova ES
  • The article is devoted to the study of immunohistochemical parameters in patients with bullous lesions of the oral mucosa. The biopsy samples of the oral mucosa were studied in 57 patients, including patients with pemphigoid bullosa (38 people) and pemphigus vulgaris (19 people). The results of immunohistochemical studies indicate the cellular mechanisms of damage to the epithelium, in which IL-1…
  • Does endoscopic sinus surgery alter the biomechanics of the orbit? [Journal Article]
    J Otolaryngol Head Neck Surg. 2020 Jun 26; 49(1):44.Sowerby LJ, Harris MS, … Moore CC
  • CONCLUSIONS: To our knowledge, this is the first demonstration that the structures removed during sinus surgery may act as a buttress for the medial orbital wall. The anatomic changes of sinus surgery may alter the biomechanics of the orbit and affect the pattern of subsequent traumatic blowout fractures.
  • Well-Being as a Precursor and Consequence of Micro-Processes in a Group Psychotherapy With Forensic Patients. [Journal Article]
    Front Psychiatry. 2020; 11:409.Bieg M, Ross T, … Fontao MI
  • Psychotherapy is an important approach for the treatment of psychiatric disorders. Apart from treating disorders as such, psychotherapy aims at increasing patients' well-being. The Therapeutic Cycles Model (TCM) is a process-oriented theoretical model that makes predictions about the psychotherapeutic progress based on verbatim content. The model helps to identify therapeutic factors on a languag…
  • [Acute fever with rash, necrosis, and bullae in both lower extremities in a 12-year-old girl]. [Case Reports]
    Zhongguo Dang Dai Er Ke Za Zhi. 2020 Jun; 22(6):651-655.Ou S, Wang X, … Liu CT
  • A girl, aged 12 years, was admitted due to fever and rash for 3 days. The child developed recurrent high fever and rash on both lower extremities 3 days before, and the rash on left lower extremity quickly merged into a patch within 24 hours, with hemorrhage and necrosis in black and purple, large vesicles, and blisters in the center. Laboratory examination showed a reduction in platelet count an…
  • Multi-omics network analysis reveals distinct stages in the human aging progression in epidermal tissue. [Journal Article]
    Aging (Albany NY). 2020 Jun 18; 12Holzscheck N, Söhle J, … Kaderali L
  • In recent years, reports of non-linear regulations in age- and longevity-associated biological processes have been accumulating. Inspired by methodological advances in precision medicine involving the integrative analysis of multi-omics data, we sought to investigate the potential of multi-omics integration to identify distinct stages in the aging progression from ex vivo human skin tissue. For t…
  • Epicardial blebs and septal hematoma after ventricular septal defect closure. [Journal Article]
    Asian Cardiovasc Thorac Ann. 2020 Jun 15 [Online ahead of print]Jose JM, Padala SRAN, … Jha AK
  • Rapidly progressive epicardial hemorrhagic blebs during weaning from cardiopulmonary bypass after perimembranous ventricular septal defect closure has not been reported previously. Here, we describe the case of a 3-month-old baby with life-threatening epicardial hemorrhagic blebs and an interventricular septal hematoma after perimembranous ventricular septal defect patch closure.
  • Eosinophils in Bullous Pemphigoid. [Journal Article]
    Panminerva Med. 2020 Jun 12 [Online ahead of print]Jones VA, Patel PM, Amber KT
  • Bullous pemphigoid (BP) is an autoimmune blistering disorder with substantial morbidity and mortality. BP is regarded as a disorder driven by IgG due to BP180 and BP230 IgG autoantibodies, yet, new advances highlight the function of eosinophils and IgE autoantibodies in BP. Evidence supports that eosinophils are involved in BP pathogenesis, notably, these include the presence of IL-5, eotaxin, an…
  • Neutrophilic dermatosis of the dorsal hands triggered by mechanical trauma. [Letter]
    J Eur Acad Dermatol Venereol. 2020 Jun 13 [Online ahead of print]Gloor AD, Feldmeyer L, Borradori L
  • Since the first descriptions by Strutton et al., neutrophilic dermatosis of the dorsal hands (NDDH) has now been recognized as a distinctive localized form of either pustular Sweet syndrome (SS) or of bullous or ulcerative pyoderma gangrenosum (PG). Although the lesions are characteristically located on the dorsa of the hands and the fingers, additional locations may be affected.
  • [Mycosis fungoides bullosa: A rare clinical presentation]. [Case Reports]
    Ann Dermatol Venereol. 2020 Jun 09 [Online ahead of print]Juzot C, Josselin N, … Quéreux G
  • CONCLUSIONS: Cases of bullous MF are very rare. In the literature, the clinical presentation is heterogeneous, with tense or flaccid bullae that can occur on unaffected skin or on erythematous plaques. The bullae generally appear after the plaques. The histologic blister site may be subepidermal or, more rarely, intra-epidermal. The exact mechanism of blister formation is not clear. Its treatment is poorly codified but follows the usual treatment of MF in its classical form.Bullous MF is a very rare entity that can mimic autoimmune blistering disease, and this diagnosis must therefore be ruled out.
  • The relationship between clinics and the venom of the causative Amazon pit viper (Bothrops atrox). [Journal Article]
    PLoS Negl Trop Dis. 2020 Jun 08; 14(6):e0008299.Moura-da-Silva AM, Contreras-Bernal JC, … Monteiro WM
  • Snake venoms are complex mixtures of proteins with toxic activities, with many distinct isoforms, affecting different physiological targets, comprised in a few protein families. It is currently accepted that this diversity in venom composition is an adaptive advantage for venom efficacy on a wide range of prey. However, on the other side, variability on isoforms expression has implications in the…
  • The new differential diagnostic test for the lichenoid drug eruption. [Journal Article]
    Dermatol Ther. 2020 Jun 08 [Online ahead of print]Sidikov A, Zaslavsky D, … Shalaeva E
  • The differential diagnosis between lichenoid drug eruption (LDE) and lichen planus (LP) is difficult due to similar clinical and histological signs but important for treatment and prognosis. The purpose of this study was to propose the new diagnosis method for differentiate LDE from LP. During 2015-2018, 20 patients with confirmed LDE, 13 patients with LP and 134 controls were examined and treate…
  • An unusual presentation of acute onset Charcot arthropathy. [Case Reports]
    J Surg Case Rep. 2020 May; 2020(5):rjaa128.Al-Najjar A, Al Shakarchi J, … Downing R
  • Charcot arthropathy is a progressive condition primarily affecting the lower limbs in patients with diabetes mellitus. It is a rare complication of diabetic neuropathy and if left untreated can lead to severe limb destruction necessitating major amputation. Here, we report the case of a 41-year-old female who presented with rapidly progressive Charcot foot over a 10-day period, necessitating open…
  • A Case of Pulmonary Infectious Bulla Caused by Mycobacterium Avium. [Journal Article]
    J UOEH. 2020; 42(2):203-208.Morimoto T, Uchimura K, … Yatera K
  • A 37-year-old Japanese man presented with a bulla with niveau-like opacity in the right upper lung on chest radiography. Air-fluid level gradually increased despite broad-spectrum antibiotic therapy. Right upper lobectomy was performed, and epithelioid granuloma with mycobacteria was histopathologically observed. Bacterial culture of the fluid was negative, but mycobacterial culture was positive …
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