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(buprenorphine naloxone)
1,204 results
  • Current status of opioid addiction treatment and related preclinical research. [Review]
    Sci Adv 2019; 5(10):eaax9140Kreek MJ, Reed B, Butelman ER
  • Opioid use disorders (OUDs) are diseases of the brain with behavioral, psychological, neurobiological, and medical manifestations. Vulnerability to OUDs can be affected by factors such as genetic background, environment, stress, and prolonged exposure to μ-opioid agonists for analgesia. Two standard-of-care maintenance medications, methadone and buprenorphine-naloxone, have a long-term positive i…
  • Association between buprenorphine/naloxone and high-dose opioid analgesic prescribing in Kentucky, 2012-2017. [Journal Article]
    Drug Alcohol Depend 2019; 205:107606Luu H, Slavova S, … Bush H
  • CONCLUSIONS: Our results indicate a significant reciprocal relationship between HDOAP and buprenorphine/naloxone prescribing and a clinically meaningful effect of buprenorphine/naloxone prescribing on reducing HDOAP. Future studies on buprenorphine/naloxone treatment expansion should take into account this bi-directional association in the context of longitudinal data and evaluate for public health benefits beyond the reduction of HDOAP.
  • Pearls for opioid use in seriously ill patients. [Journal Article]
    J Pain Palliat Care Pharmacother 2019; :1-5Kral L, Ku J, … Fudin J
  • Opioids are often the foundation of pain management in seriously ill patients. Unfortunately, even experienced providers carry with them information that they consider "fact", when this information is not based on scientific evidence, but on "myth". Several topics were elicited based on common beliefs and misconceptions in clinical practice. These were identified via a survey of pharmacist pain a…
  • Price elasticity of demand for buprenorphine/naloxone prescriptions. [Journal Article]
    J Subst Abuse Treat 2019; 106:4-11McClellan C, Fingar KR, … Gibson TB
  • Although there have been supply-side efforts in response to the opioid crisis (e.g., prescription drug monitoring programs), little information exists on demand-side approaches related to patient cost sharing that may affect utilization of and adherence to pharmacotherapy by individuals with opioid use disorder. Among individuals who had initiated pharmacotherapy, we estimated the price elasticit…
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