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36,781 results
  • Newly formulated 5% 5-aminolevulinic acid phototherapy on Candida albicans. [Journal Article]
    Photodiagnosis Photodyn Ther 2019Greco G, Di Piazza S, … Amaroli A
  • CONCLUSIONS: The 5%ALA-PTt preparation was shown to be effective in reducing the growth of biofilm and inoculum of C. albicans. This effect seems to be linked to the intrinsic characteristics of 5%ALA-TPt, such acidic pH and the induction of free radical production. This outcome was significantly enhanced by the effect of PT at relatively short incubation and irradiation times, which resulted in growth inhibition of both treated biofilm and inoculum by ⿼80% and ⿼95%, respectively.
  • Pyonitrins A-D: Chimeric natural products produced by Pseudomonas protegens. [Journal Article]
    J Am Chem Soc 2019Mevers E, Saurí J, … Clardy J
  • Bacterial symbionts frequently provide chemical defenses for their hosts, and such systems can provide discovery pathways to new antifungals and structurally intriguing metabolites. This report describes a small family of naturally-occurring small molecules with chimeric structures and a mixed biosynthesis that features an unexpected but key non-enzymatic step. An insect-associated Pseudomonas pr…
  • Celiac disease in the context of airborne allergen-associated chronic vulvo-vaginitis. [Journal Article]
    Eur Rev Med Pharmacol Sci 2019; 23(18):8084-8086Theodoropoulos DS, Kelly LE, Stockdale CK
  • We present a woman with a three-year history of severe chronic urticaria and recurrent vulvo-vaginal Candidiasis in the setting of seasonal allergic rhinitis. Her past medical history was significant only for Bell's palsy in her childhood. Her review of systems was otherwise negative (specifically: no history of diarrhea, weight loss, malabsorption, anemia, nor eczema). Extensive testing revealed…
  • Microbial Interactions in Oral Communities Mediate Emergent Biofilm Properties. [Journal Article]
    J Dent Res 2019; :22034519880157Diaz PI, Valm AM
  • Oral microbial communities are extraordinarily complex in taxonomic composition and comprise interdependent biological systems. The bacteria, archaea, fungi, and viruses that thrive within these communities engage in extensive cell-cell interactions, which are both beneficial and antagonistic. Direct physical interactions among individual cells mediate large-scale architectural biofilm arrangemen…
  • Delay in the Diagnosis of APECED: A Case Report and Review of Literature from Iran. [Journal Article]
    Immunol Invest 2019; :1-8Jamee M, Mahdaviani SA, … Velayati A
  • Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) syndrome is a rare monogenic autosomal recessive disorder caused by biallelic mutations in the AIRE (autoimmune regulator) gene. Patients with APECED present with heterogeneous endocrine and non-endocrine manifestations. In this study, we report an Iranian patient who presented with Addison disease, chronic mucocutaneous cand…
  • Management of congenital cutaneous candidiasis in a healthy term baby: A case report. [Case Reports]
    SAGE Open Med Case Rep 2019; 7:2050313X19876707Colantonio S, Hedin E, … Gavigan G
  • The management of congenital cutaneous candidiasis in a healthy term neonate of normal birth weight is unclear. Often, healthy term neonates undergo extensive evaluation followed by systemic treatment, which may not be clinically warranted. Here, we present a case of a healthy term neonate with congenital cutaneous candidiasis, whose work-up was minimally invasive and was successfully treated wit…
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