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7,405 results
  • Resistance against Trichinella spiralis infection in pups delivered by T. spiralis-infected dam. [Journal Article]
    Vet Parasitol 2019; 273:60-66Chu KB, Lee HA, … Quan FS
  • Maternal antibody transmission via placenta and breastmilk are known to confer protection in infants. In this study, we investigated the maternal immunity transmission in pups delivered by rats infected with Trichinella spiralis and assessed the resulting resistance against subsequent parasitic infection. Our results revealed that parasite-specific IgG, IgG1 and IgG2a antibodies were present in p…
  • The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function. [Journal Article]
    Nat Commun 2019; 10(1):2344Bancroft AJ, Levy CW, … Grencis RK
  • Infection by soil transmitted parasitic helminths, such as Trichuris spp, are ubiquitous in humans and animals but the mechanisms determining persistence of chronic infections are poorly understood. Here we show that p43, the single most abundant protein in T. muris excretions/secretions, is non-immunogenic during infection and has an unusual sequence and structure containing subdomain homology t…
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