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13,672 results
  • Normal Aging and Its Role in Cancer Metastasis. [Journal Article]
    Cold Spring Harb Perspect Med 2019Fane M, Weeraratna AT
  • Metastasis is the most common cause of death, with treatments failing to provide a durable response. Aging is a key prognostic factor in many cancers. Emerging data suggest that normal age-related changes in the tumor microenvironment can contribute to metastatic progression. These changes encompass secreted factors, biophysical changes, and changes in both stromal and immune cell populations. Th…
  • Egg yolk-free cryopreservation of bull semen. [Journal Article]
    PLoS One 2019; 14(10):e0223977Anzar M, Rajapaksha K, Boswall L
  • Egg yolk is a common ingredient of mammalian semen extender to protect sperm against initial cold shock. However, egg yolk has biosecurity risks. Our main objectives were to cryopreserve bull semen without egg yolk using exogenous cholesterol and to study the protective role of glycerol in egg yolk-free semen extender. Other objectives were to compare protein profiles and in vitro fertilization p…
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