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797 results
  • Opioid analgesics are the leading cause of adverse drug reactions in the obstetric population in South Korea. [Journal Article]
    Medicine (Baltimore) 2019; 98(21):e15756Choi SK, Kim YH, … Park IY
  • Medication use during pregnancy is gradually increasing; however, the safety of this practice remains largely unknown.We investigated medications with the most adverse drug reactions (ADRs) among pregnant women and the clinical features of those medications.Reports of ADRs among pregnant women were extracted from the Korea Adverse Events Reporting System (January 2012-December 2015). We analyzed …
  • Maternal anaphylactic shock in pregnancy: A case report. [Case Reports]
    Medicine (Baltimore) 2018; 97(37):e12351Jeon HJ, Ryu A, … Kim NS
  • CONCLUSIONS: This is the first reported case of anaphylaxis following cefotetan administration in pregnancy. Cefotetan, a second-generation cephalosporin, is a commonly prescribed antibiotic used to treat a wide range of bacterial infections. The case demonstrated life-threatening anaphylactic reaction during pregnancy. Even a skin test using antibiotics alone triggered anaphylaxis.
  • Cefotetan-Induced Hemolytic Anemia: Case Series and Review. [Journal Article]
    J Pharm Pract 2018; :897190018798198Lim K, Tran H, … Klapper E
  • CONCLUSIONS: Five cases of cefotetan-induced hemolytic anemia, which presented over the period of a single year at our center, are described. In each case, hemolytic anemia was confirmed by testing for the presence of anti-cefotetan antibodies. Each case occurred approximately 1 to 2 weeks following exposure to the drug. All five patients survived. A brief review of drug-induced immune hemolytic anemia (DIIHA) is also discussed.DIIHA may be difficult to distinguish from other causes of hemolytic anemia, but should be included in the differential in patients exposed to medications associated with DIIHA. Once suspected, antibody testing should be performed, and once diagnosed, further exposure should be avoided.
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