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430,906 results
  • [Mechanisms of electroacupuncture for improving Alzheimer's disease from reducing β amyloid protein level]. [Review]
    Zhen Ci Yan Jiu. 2020 May 25; 45(5):426-31.Yang WD, Dong WG
  • Alzheimer's disease (AD), a neurodegenerative disorder characterized by amyloid deposits and neurofibrillary degeneration, is the most common type of dementia and has no incurable therapies at the moment. Electroacupuncture (EA) therapy has been widely used in clinical treatment of AD, and has attained approving effects. This article reviews the development of researches on the mechanisms of EA u…
  • Corticospinal Wallerian Degeneration Before Myelination: A Case Report. [Journal Article]
    Pediatr Dev Pathol. 2020 May 14 [Online ahead of print]Szymanski LJ, Hawes D, Gilles F
  • Wallerian degeneration is defined as axonal fiber and myelin sheath degeneration that affects myelinated axons within the peripheral or central nervous system. Wallerian degeneration or anterograde axonal degeneration before myelination is rarely reported. Involvement of both corticospinal tracts (CSTs) is rarely documented in the literature. We present the postmortem neuropathologic findings of …
  • Cerebellum: What is in a Name? Historical Origins and First Use of This Anatomical Term. [Journal Article]
    Cerebellum. 2020 May 13 [Online ahead of print]Voogd J, De Zeeuw CI
  • In this paper, we study who first used the Latin anatomical term "cerebellum" for the posterior part of the brain. The suggestion that this term was introduced by Leonardo da Vinci is unlikely. Just before the start of the da Vinci era in the fifteenth century, several authors referred to the cerebellum as "cerebri posteriorus." Instead, in his translation of Galen's anatomical text De utilitare …
  • Detection of Astrovirus in a Cow with Neurological Signs by Nanopore Technology, Italy. [Journal Article]
    Viruses. 2020 May 11; 12(5)Zaccaria G, Lorusso A, … Marcacci M
  • In this study, starting from nucleic acids purified from the brain tissue, Nanopore technology was used to identify the etiological agent of severe neurological signs observed in a cow which was immediately slaughtered. Histological examination revealed acute non-suppurative encephalomyelitis affecting the brainstem, cerebrum, cerebellum, and medulla oblongata, while by using PCR-based assays, th…
  • Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease. [Case Reports]
    N Engl J Med. 2020 05 14; 382(20):1926-1932.Schweitzer JS, Song B, … Kim KS
  • We report the implantation of patient-derived midbrain dopaminergic progenitor cells, differentiated in vitro from autologous induced pluripotent stem cells (iPSCs), in a patient with idiopathic Parkinson's disease. The patient-specific progenitor cells were produced under Good Manufacturing Practice conditions and characterized as having the phenotypic properties of substantia nigra pars compact…
  • Jump-Starting Evolution. [Journal Article]
    Cerebrum. 2020 Mar-Apr; 2020Dugatkin LA
  • Since How to Tame a Fox (and Build a Dog) appeared in 2017, molecular genetics research connected to the silver fox domestication experiment has been published in Nature and Proceedings of the National Academy of Science. Lee Alan Dugatkin writes about his connection to the project, the role of neural crest cells in domesticating foxes, and how dogs, bonobos, and humans fit into the picture.
  • Decoding the Canine Mind. [Journal Article]
    Cerebrum. 2020 Mar-Apr; 2020Berns G
  • Our author, the Distinguished Professor of Neuroeconomics at Emory University and co-founder of Dog Star Technologies-a company using neuroscience to enhance the dog-human partnership-has put more than 100 dogs through a brain scanner. His article addresses a dog's perception of the world, social cognition findings, canine mental health, and more.
  • The intracranial vasculature of canines represents a model for neurovascular ischemia and training residents and fellows in endovascular neurosurgery. [Journal Article]
    Neuroradiol J. 2020 May 05 [Online ahead of print]Lv X, Li C, Jiang W
  • CONCLUSIONS: Unique amenability of the canine intracranial vasculature to selective and microcatheter cannulation renders experimentally induced cerebral, cerebellar, and brainstem via occlusion of the supratentorial and infratentorial arteries a simple matter. The neural vasculature irrigating the canine cerebrum, brainstem, and cerebellum may consequently prove useful in helping young and nascent endovascular neurosurgeons in developing and refining their skills of microcatheter navigation and manipulation and deployment of therapeutic devices to achieve effective occlusion of aneurysms, arteriovenous malformations, arteriovenous fistulas, and neoplasms of the intracranial cavity.
  • Roles of the Cerebellum in Motor Preparation and Prediction of Timing. [Review]
    Neuroscience. 2020 Apr 30 [Online ahead of print]Tanaka M, Kunimatsu J, … Takeya R
  • The cerebellum is thought to have a variety of functions because it developed with the evolution of the cerebrum and connects with different areas in the frontoparietal cortices. Like neurons in the cerebral cortex, those in the cerebellum also exhibit strong activity during planning in addition to the execution of movements. However, their specific roles remain elusive. In this article, we revie…
  • Cypermethrin-induced cortical neurons apoptosis via the Nrf2/ARE signaling pathway. [Journal Article]
    Pestic Biochem Physiol. 2020 May; 165:104547.Zhou L, Zhou M, … Xiao M
  • Pesticide residue is a common problem worldwide. Cypermethrin is a type II pyrethroid pesticide that has been widely used in recent years. It has become a widespread residual pesticide in the environment and agricultural products. The neurotoxicity of cypermethrin remains a matter of concern. However, few studies have evaluated its toxicity on cerebral cortical neurons. As the center of the nervo…
  • Breast Metastasis From a Non-small Cell Lung Cancer: A Case Report. [Case Reports]
    Cureus. 2020 Mar 29; 12(3):e7460.Guerrouaz MA, Samba S, … Mezouar L
  • Although primary breast cancer (BC) is the most frequent cancer in the world, their mammary metastases are rare. In this paper, we report the case of a 51-year-old male patient diagnosed with a mammary lump and an intracranial hypertension syndrome. Mammography showed the presence of an irregular opacity without microcalcifications. After a cytological and immunohistochemical examination, the bre…
  • The brain of Cataglyphis ants: neuronal organization and visual projections. [Journal Article]
    J Comp Neurol. 2020 Apr 26 [Online ahead of print]Habenstein J, Amini E, … Rössler W
  • Cataglyphis ants are known for their outstanding navigational abilities. They return to their inconspicuous nest after far-reaching foraging trips using path integration, and whenever available, learn and memorize visual features of panoramic sceneries. To achieve this, the ants combine directional visual information from celestial cues and panoramic scenes with distance information from an intri…
  • Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms. [Journal Article]
    J Neurosci. 2020 May 20; 40(21):4103-4115.Wang HY, Eguchi K, … Takahashi T
  • Volatile anesthetics are widely used for surgery, but neuronal mechanisms of anesthesia remain unidentified. At the calyx of Held in brainstem slices from rats of either sex, isoflurane at clinical doses attenuated EPSCs by decreasing the release probability and the number of readily releasable vesicles. In presynaptic recordings of Ca2+ currents and exocytic capacitance changes, isoflurane atten…
  • Brain-Wide Mapping of Afferent Inputs to Accumbens Nucleus Core Subdomains and Accumbens Nucleus Subnuclei. [Journal Article]
    Front Syst Neurosci. 2020; 14:15.Ma L, Chen W, … Han Y
  • The nucleus accumbens (NAc) is the ventral part of the striatum and the interface between cognition, emotion, and action. It is composed of three major subnuclei: i.e., NAc core (NAcC), lateral shell (NAcLS), and medial shell (NAcMS), which exhibit functional heterogeneity. Thus, determining the synaptic inputs of the subregions of the NAc is important for understanding the circuit mechanisms inv…
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