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Unbound Medicine.
(chemistry)
4,626,225 results
  • Establishment of a Mouse Model for Post-Inflammatory Hyperpigmentation. [Journal Article]
    Pigment Cell Melanoma Res. 2020 Jul 04 [Online ahead of print]Nakano S, Abe Y, … Suzuki T
  • Post-inflammatory hyperpigmentation (PIH) is a common cutaneous condition that can cause a disfigured appearance. However, the pathophysiology of PIH remains poorly understood, at least in part, because an appropriate animal model for research has not been established. In order to analyze the pathomechanism of PIH, we successfully induced PIH in a hairless version of transgenic mice (hk14-SCF Tg/…
  • Release behavior of metals from tin-lined copper cookware into food simulants during cooking and cold storage. [Journal Article]
    Environ Sci Pollut Res Int. 2020 Jul 05 [Online ahead of print]Banavi P, Sadeghi E, … Rouhi M
  • The copper pots with an inner coating layer of tin have been remarkably used in many countries for a long time. In this study, leaching of some metals from tin-lined copper pots into food simulators at different pHs (4, 5.5, 7, and 8.5) during boiling processing (95 °C for 1, 2, and 3 h) or refrigerated storage (4 °C for 1, 2, and 3 days) was investigated. Citric acid and sodium hydroxide were us…
  • The effects of a short-term exposure to propiconazole in zebrafish (Danio rerio) embryos. [Journal Article]
    Environ Sci Pollut Res Int. 2020 Jul 04 [Online ahead of print]Zhao F, Cao F, … Qiu L
  • Propiconazole (PCZ) is a widely used fungicide around the world and was frequently detected in surface waters, which would pose risk to aquatic organisms. Previous studies indicated that PCZ has high toxicity to different kinds of fish. However, most of the studies focus on the toxicity and mechanisms of PCZ to adult fish, the potential toxicity mechanism of PCZ to fish embryos is still poorly un…
  • The cadmium tolerance development of poplar callus is influenced by silicon. [Journal Article]
    Ecotoxicology. 2020 Jul 04 [Online ahead of print]Labancová E, Vivodová Z, … Kollárová K
  • Cadmium-tolerant plants were studied for their possible usage in phytoremediation techniques. However, their response to cadmium cations at a cellular level has not been properly studied. Silicon is a beneficial element that seems to change the plant's response to the Cd2+ presence. The aim of the present study was to investigate the Cd2+ tolerance patterns of poplar callus cells exposed to Cd+2 …
  • Extrahepatic metabolism of ibrutinib. [Journal Article]
    Invest New Drugs. 2020 Jul 04 [Online ahead of print]Rood JJM, Jamalpoor A, … Sparidans RW
  • Ibrutinib is a first-in-class Bruton's kinase inhibitor used in the treatment of multiple lymphomas. In addition to CYP3A4-mediated metabolism, glutathione conjugation can be observed. Subsequently, metabolism of the conjugates and finally their excretion in feces and urine occurs. These metabolites, however, can reach substantial concentrations in human subjects, especially when CYP3A4 is inhibi…
  • Cooperative foraging during larval stage affects fitness in Drosophila. [Journal Article]
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 Jul 04 [Online ahead of print]Dombrovski M, Kuhar R, … Condron B
  • Cooperative behavior can confer advantages to animals. This is especially true for cooperative foraging which provides fitness benefits through more efficient acquisition and consumption of food. While examples of group foraging have been widely described, the principles governing formation of such aggregations and rules that determine group membership remain poorly understood. Here, we take adva…
  • Selected essential oils and their mechanisms for therapeutic use against public health disorders. An overview. [Review]
    Z Naturforsch C J Biosci. 2020 Jul 06 [Online ahead of print]Leherbauer I, Stappen I
  • Today, the numbers of people suffering from lifestyle diseases like diabetes, obesity, allergies and depression increases mainly in industrialised states. That does not only lower patients' quality of life but also severely stresses the health care systems of these countries. Essential oils (EO) have been in use as therapeutic remedies for centuries against various complaints, but still their eff…
  • Use of ultrasound at a pilot scale to accelerate the ageing of sherry vinegar. [Journal Article]
    Ultrason Sonochem. 2020 Jul 01; 69:105244.Jiménez-Sánchez M, Durán-Guerrero E, … Castro R
  • In the present work, the accelerated ageing process of sherry vinegar has been studied at pilot scale by means of the joint application of ultrasound, micro-oxygenation and wood chips (American oak, French oak and Spanish oak). The CIELab parameters have been studied as well as the polyphenolic and volatile content of the aged vinegar samples. Vinegars aged with American oak presented different c…
  • Electron Transport Chain Complex II Regulates Steroid Metabolism. [Journal Article]
    iScience. 2020 Jun 20; 23(7):101295.Bose HS, Marshall B, … Whittal RM
  • The first steroidogenic enzyme, cytochrome P450-side-chain-cleavage (SCC), requires electron transport chain (ETC) complexes III and IV to initiate steroid metabolic processes for mammalian survival. ETC complex II, containing succinate dehydrogenase (quinone), acts with the TCA cycle and has no proton pumping capacity. We show that complex II is required for SCC activation through the proton pum…
  • Developing a new chemosensor targeting zinc ion based on two types of quinoline platform. [Journal Article]
    Spectrochim Acta A Mol Biomol Spectrosc. 2020 Jun 26; 241:118652.Kim A, Lee H, … Kim C
  • A chemosensor DQ (2-(2-(quinolin-2-yl)hydrazinyl)-N-(quinolin-8-yl)acetamide), based on two quinoline moieties, has been synthesized. DQ could detect zinc ion through fluorescence turn-on in aqueous media. Limit of detection was calculated as 0.07 μM, far lower than the standard of WHO for zinc ion. The practicality of DQ was demonstrated via the successful results of reusability with EDTA, easy …
  • A new whole-cell biocatalyst for sulfur dioxide filtering and degradation. [Journal Article]
    Bioresour Technol. 2020 Jun 30; 314:123755.Haghighatian S, Mazarei E, … Memarpoor-Yazdi M
  • In this study, the interaction of the magnetotactic bacterium with sulfite compounds and their potential to degrade SO2 was investigated using cyclic voltammetry (CV), molecular emission cavity analysis (MECA) and ion-exchange chromatography (IEC). This biofilter was able to degrade SO2 up to 22281 mg m-3 by disproportionation reaction and the formation of S2- and SO42- with ≥99% efficiency. Desi…
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