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18,765 results
  • Synapsin I Synchronizes GABA Release in Distinct Interneuron Subpopulations. [Journal Article]
    Cereb Cortex 2019Forte N, Binda F, … Baldelli P
  • Neurotransmitters can be released either synchronously or asynchronously with respect to action potential timing. Synapsins (Syns) are a family of synaptic vesicle (SV) phosphoproteins that assist gamma-aminobutyric acid (GABA) release and allow a physiological excitation/inhibition balance. Consistently, deletion of either or both Syn1 and Syn2 genes is epileptogenic. In this work, we have chara…
  • Expression of type I mGluRs Predicts Plasticity in the Hippocampal Stratum Radiatum Interneurons. [Journal Article]
    Neurosci Lett 2019; :134472Nufer TM, Merrill C, … Edwards JG
  • Changes in synaptic strength between hippocampal CA1 pyramidal cell synapses are partly responsible for memory acquisition. This plasticity is modulated by feedforward inhibitory interneurons in the stratum radiatum. While radiatum interneurons experience either long-term depression (LTD), short-term depression (STD), or lack plasticity, it is unclear whether plasticity correlates to specific int…
  • Quantitation and chemical coding of enteroendocrine cell populations in the human jejunum. [Journal Article]
    Cell Tissue Res 2019Fazio Coles TE, Fothergill LJ, … Furness JB
  • Recent studies reveal substantial species and regional differences in enteroendocrine cell (EEC) populations, including differences in patterns of hormone coexpression, which limit extrapolation between animal models and human. In this study, jejunal samples, with no histologically identifiable pathology, from patients undergoing Whipple's procedure were investigated for the presence of gastroint…
  • Interaction between genes involved in energy intake regulation and diet in obesity. [Review]
    Nutrition 2019; 67-68:110547Crovesy L, Rosado EL
  • Obesity is a multifactorial, complex, and public health problem worldwide. Interaction between genes and environment as associated with diet may predispose an individual to obesity. In this sense, nutrigenetics appears to be a strategy that can improve understanding of the gene-diet interaction. The aim of this literature review was to summarize data from studies of genes involved in the regulati…
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