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(chorionic villi)
7,037 results
  • Can cell-free DNA testing be used in pregnancies with increased nuchal translucency? [Journal Article]
  • UOUltrasound Obstet Gynecol 2019 Jul 13
  • Miranda J, Paz Y Miño F, … Borrell A
  • CONCLUSIONS: cfDNA does not appear to be the appropriate genetic test in fetuses with a NT above the 99th centile, given that 12-19% of the genetic anomalies were undetectable with the current tests. Additionally, 6.6% of fetuses will have a major structural abnormality identifiable using first-trimester ultrasound. This article is protected by copyright. All rights reserved.
  • Patterns of Placental Injury in Congenital Anomalies in Second Half of Pregnancy. [Journal Article]
  • PDPediatr Dev Pathol 2019 May 28; :1093526619852869
  • Stanek J
  • CONCLUSIONS: Fetal anomalies in second half of pregnancy feature abnormal clinical phenotypes much more frequently than abnormal placental phenotypes. Chromosomal abnormalities with or without heart malformations tend to feature villous edema, and erythroblastosis of fetal blood, likely due to fetal heart failure. Mass-forming fetal anomalies feature placental histological lesions of shallow placental implantation, diffuse chronic hypoxic patterns of placental injury, and lesions of fetal vascular malperfusion, likely stasis-induced.
  • [Genetic testing of chorionic villi from abortuses during early pregnancy]. [Journal Article]
  • ZYZhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 Jun 10; 36(6):547-551
  • Yang Y, Qu S, … Kong X
  • CONCLUSIONS: Chromosomal abnormalities are the main cause for early miscarriage, among which aneuploidies are most common. The prevalence of aneuploidies is significantly increased among women over 35. SNP-array analysis has the advantage of high success rate, high resolution and great accuracy, but the clinical significance of microdeletions/microduplications found by SNP-array can be difficult for interpretation.
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