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(chromium 51)
784 results
  • Serial blood volume estimation in rabbits using trivalent chromium - An exploratory study. [Journal Article]
    MethodsX 2019; 6:1068-1071Baby PM, Kumar P, … Bhat NB
  • Though often used in cardiac intensive monitoring set up, simultaneous evaluation of several variables like CVP, PCWP, SVV and hTEE for fluid volume resuscitation (especially when capillary permeability is major problem than cardiac performance) is a major challenge in many ICU setups. Therefore, repetitive determination of blood volume by trivalent chromium [51Cr (III)] as a direct single variab…
  • Measuring natural killer cell cytotoxicity by flow cytometry. [Journal Article]
    Pathology 2019; 51(3):286-291Wong WY, Wong H, … Chan E
  • Natural killer (NK) cell cytotoxic function is critical in guarding an organism against viral infections and malignantly transformed cells. Although the 51Chromium (51Cr)-release assay is regarded as the gold standard for assessing NK cell cytolytic activity, this method is associated with a number of technical problems including the use of radioactive reagents and inconsistent assay performance,…
  • Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Chromium Release Assay. [Journal Article]
    Methods Mol Biol 2019; 1913:167-179van der Haar Àvila I, Marmol P, … Pico de Coaña Y
  • Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism in which immune cell activation is induced by the cross-linking of CD16 with the Fc region of antibodies that at the same time bind specifically to cell surface antigens. ADCC stimulates the secretion of perforin, granzymes, and cytokines leading to lysis of the malignant cells. Natural killer (NK) cells express the CD16 receptor…
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