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79 results
  • In vitro characterization and genetic diversity of Bordetella avium field strains. [Journal Article]
    Avian Pathol 2020; 49(1):36-46Knab R, Petersen H, … Jung A
  • Bordetella avium (BA) is a respiratory pathogen of particular importance for turkeys. Specific adherence and damage to the respiratory epithelia are crucial steps of the pathogenesis, but knowledge about the mechanisms and the variety of virulence in field strains is limited. We analysed 17 BA field strains regarding their in vitro virulence-associated properties in tracheal organ cultures (TOC) …
  • Ciliostasis of airway epithelial cells facilitates influenza A virus infection. [Journal Article]
    Vet Res 2018; 49(1):65Fu Y, Tong J, … Herrler G
  • Porcine precision-cut lung slices (PCLS) were used to analyze the effect of the ciliary activity on infection of airway epithelial cells by influenza viruses. Treatment of slices with 2% NaCl for 30 min resulted in reversible ciliostasis. When PCLS were infected by a swine influenza virus of the H3N2 subtype under ciliostatic conditions, the viral yield was about twofold or threefold higher at 24…
  • Comparative Evaluation of the Pathogenicity of Mycoplasma gallinaceum in Chickens. [Journal Article]
    Avian Dis 2018; 62(1):50-56Adeyemi M, Bwala DG, Abolnik C
  • Mycoplasma gallinaceum is not among the most pathogenic mycoplasmas affecting poultry, but its continuous re-isolation from flocks in South Africa displaying typical signs of mycoplasmosis prompted us to revisit its role in respiratory disease. Specific-pathogen-free white leghorn chickens were co-challenged with either M. gallinaceum (MGC) and QX-like infectious bronchitis virus (IBV), or the mo…
  • In vitro evaluation of nasal mucociliary clearance using excised rat nasal septum. [Journal Article]
    Biol Pharm Bull 2012; 35(6):889-94Inoue D, Furubayashi T, … Higashi Y
  • Mucus on the nasal mucosa is translocated to the pharynx by ciliary beating, which is an important nonspecific defense mechanism called mucociliary clearance (MC). MC is one of the important factors determining the rate and extent of drug absorption after nasal application. The purpose of this study is to evaluate MC using rat nasal septum under physiological condition in an in vitro system. The …
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