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12,555 results
  • Understanding hydrogen-bonding structures of molecular crystals via electron and NMR nanocrystallography. [Journal Article]
    Nat Commun 2019; 10(1):3537Guzmán-Afonso C, Hong YL, … Nishiyama Y
  • Understanding hydrogen-bonding networks in nanocrystals and microcrystals that are too small for X-ray diffractometry is a challenge. Although electron diffraction (ED) or electron 3D crystallography are applicable to determining the structures of such nanocrystals owing to their strong scattering power, these techniques still lead to ambiguities in the hydrogen atom positions and misassignments …
  • Vitamin B12 Prevents Cimetidine-Induced Androgenic Failure and Damage to Sperm Quality in Rats. [Journal Article]
    Front Endocrinol (Lausanne) 2019; 10:309Beltrame FL, de Santi F, … Sasso-Cerri E
  • Cimetidine, used as an anti-ulcer and adjuvant treatment in cancer therapy, causes disorders in the male reproductive tract, including steroidogenesis. However, its effect on sperm quality and male fertility has been poorly addressed. Since vitamin B12 has demonstrated to recover spermatogonia number and sperm concentration in cimetidine-treated rats, we evaluated the impact of cimetidine on sper…
  • Adrenal insufficiency from steroid-containing complementary therapy: importance of detailed history [Journal Article]
    Endocrinol Diabetes Metab Case Rep 2019; 2019(1):1-4Kempegowda P, Quinn L, … Bates A
  • A 62-year-old Asian British female presented with increasing tiredness. She had multiple co-morbidities and was prescribed steroid inhalers for asthma. She had also received short courses of oral prednisolone for acute asthma exacerbations in the last 2 years. Unfortunately, the frequency and dose of steroids for asthma was unclear from history. Her type 2 diabetes mellitus (DM) control had deter…
  • StatPearls: Cimetidine [BOOK]
    StatPearls Publishing: Treasure Island (FL) Pino Maria A. MA Azer Samy A. SA King Saud University, King Khalid UH BOOK
  • Cimetidine is a gastric acid reducer used in the short-term treatment of duodenal and gastric ulcers.[1] The drug is effective in managing gastric hypersecretion, and therefore, used for the management of reflux esophagitis disease and in the prevention of stress ulcers. With the development of proton pump inhibitors, such as omeprazole, approved for the same indications, cimetidine is available …
  • Pharmacological Characterization of Mouse Hind Paw Edema Induced by Parachartergus fraternus Venom. [Journal Article]
    Inflammation 2019de Araujo Isaias Muller J, Mortari MR, … Toffoli-Kadri MC
  • Stings from the wasp Parachartergus fraternus occur throughout Latin America, and edema followed by pain is the main symptom presented by victims. This often limited inflammatory event has not been characterized for this species. In this work, we identified the mechanisms and possible mediators involved in this response. P. fraternus venom (100, 200, and 400 μg/kg) was injected into the hind paws…
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