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7,676 results
  • Altered plasma levels of arginine metabolites in depression. [Journal Article]
    J Psychiatr Res 2019; 120:21-28Ozden A, Angelos H, … John P
  • L-Arginine pathway metabolites appear to play differential roles in the pathogenesis of major depressive disorder (MDD). Studies have revealed an antidepressant and anxiolytic effect of agmatine and putrescine. Possible mechanisms of these effects include inhibition of nitric oxide synthase and N-methyl-D-aspartate receptors. The present study sought to determine whether MDD is associated with al…
  • Chemokine CXCb1 stimulates formation of NETs in trunk kidney neutrophils of common carp. [Journal Article]
    Dev Comp Immunol 2019; :103521Pijanowski L, Kemenade BMLV, Chadzinska M
  • Both in mammals and in fish, CXC chemokines activate leukocytes and regulate their migration both under normal physiological and inflammatory conditions. Moreover, in mammalian neutrophils CXC chemokines also stimulate the formation of neutrophil extracellular traps (NETs). Here, we investigated the effects of recombinant carp CXCL8s and CXCb1 on NET formation in neutrophils from the head (HK) an…
  • Sensing of citrulline modifications in histone peptides by deep cavitand hosts. [Journal Article]
    Chem Commun (Camb) 2019Gill AD, Hickey BL, … Hooley RJ
  • Arrayed cavitand:fluorophore sensor complexes can selectively sense small citrulline modifications at arginine residues on post-translationally modified peptides. The sensor can differentiate between different numbers of citrulline modifications, and a simple two-fluorophore, 6-component array can effect cross-reactive discrimination between single modifications in aqueous solution.
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