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Unbound Medicine.
(cocoon strategy)
102 results
  • Actin Assembly around the Shigella-Containing Vacuole Promotes Successful Infection. [Journal Article]
    Cell Rep. 2020 May 12; 31(6):107638.Kühn S, Bergqvist J, … Enninga J
  • The enteroinvasive bacterium Shigella flexneri forces its uptake into non-phagocytic host cells through the translocation of T3SS effectors that subvert the actin cytoskeleton. Here, we report de novo actin polymerization after cellular entry around the bacterium-containing vacuole (BCV) leading to the formation of a dynamic actin cocoon. This cocoon is thicker than any described cellular actin s…
  • Abdominal cocoon: an unexpected cause of ascites in a healthy patient. [Case Reports]
    J Surg Case Rep. 2019 Dec; 2019(12):rjz310.Kappauf C, Rahaman J, Popowich D
  • Abdominal cocoon is the idiopathic fibrotic encasement of abdominal organs. It classically presents as small bowel obstruction in young women. In this case report, we present a rare example of a patient presenting solely with massive ascites of presumed gynecologic origin, who upon surgical exploration was found to have abdominal cocoon. We discuss the patient's unique disease presentation, unrev…
  • Strategies for controlling egress of therapeutic cells from hydrogel microcapsules. [Journal Article]
    J Tissue Eng Regen Med. 2019 04; 13(4):612-624.Benavente-Babace A, Haase K, … Godin M
  • Endothelial progenitor cells and human mesenchymal stem cells (hMSCs) have shown great regenerative potential to repair damaged tissue; however, their injection in vivo results in low retention and poor cell survival. Early clinical research has focussed on cell encapsulation to improve viability and integration of delivered cells. However, this strategy has been limited by the inability to repro…
  • An efficient method for multigene co-interference by recombinant Bombyx mori nucleopolyhedrovirus. [Journal Article]
    Mol Genet Genomics. 2019 Feb; 294(1):111-120.Zheng H, Ren F, … Sun J
  • Bombyx mori Nucleopolyhedrovirus (BmNPV), which is a member of the Baculoviridae family, is a significant pathogen of the silkworm. The infection of BmNPV is often lethal and causes about 20% loss of cocoon in the silk industry annually. To explore the effects of different gene inhibition strategies on the replication cycle of baculovirus, we constructed the mutant virus to infect BmN cells direc…
  • [Recognition of the diagnosis and treatment of small intestinal obstruction]. [Journal Article]
    Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Oct 25; 20(10):1136-1140.Chen Q, Jiang J
  • Small intestinal obstruction is a common and frequent disease in general surgery. Delayed diagnosis and surgical timing, and inaccurate treatment strategy will lead to life-threatening complications. Therefore, how to diagnose and treat quickly and accurately is still a difficult problem in current gastrointestinal surgery. This paper summarizes and analyzes the diagnosis and treatment strategies…
  • Independent tuning of size and coverage of supported Pt nanoparticles using atomic layer deposition. [Journal Article]
    Nat Commun. 2017 10 20; 8(1):1074.Dendooven J, Ramachandran RK, … Detavernier C
  • Synthetic methods that allow for the controlled design of well-defined Pt nanoparticles are highly desirable for fundamental catalysis research. In this work, we propose a strategy that allows precise and independent control of the Pt particle size and coverage. Our approach exploits the versatility of the atomic layer deposition (ALD) technique by combining two ALD processes for Pt using differe…
  • Tissue-specific genome editing of laminA/C in the posterior silk glands of Bombyx mori. [Journal Article]
    J Genet Genomics. 2017 Sep 20; 44(9):451-459.Liu Y, Ma S, … Xia Q
  • The RNA-guided CRISPR/Cas9 system has been shown to be a powerful tool for genome editing in various organisms. A comprehensive toolbox for multiplex genome editing has been developed for the silkworm, Bombyx mori, a lepidopteran model insect of economic importance. However, as previous methods mainly relied on delivery of transient Cas9/guide RNA (gRNA), they could not be used in loss-of-functio…
  • Epidemiological factors related to hospitalization due to influenza in children below 6 months of age. [Journal Article]
    Eur J Pediatr. 2017 Oct; 176(10):1425-1428.Bustamante J, Calzado I, … Méndez-Echevarría A
  • CONCLUSIONS: This study underlines the importance of increasing influenza immunization among household contacts of infants below 6 months to prevent their influenza admission. What is Known: • Infants younger than 6 months old are considered a high-risk population. • Vaccination against influenza is not licensed in infants below 6 months. What is New: • Increasing vaccination coverage in elderly people could reduce infants' hospitalization rates. • Cocoon immunization strategy may reduce the admission of infants.
  • Atomic Layer Deposition Route To Tailor Nanoalloys of Noble and Non-noble Metals. [Journal Article]
    ACS Nano. 2016 09 27; 10(9):8770-7.Ramachandran RK, Dendooven J, … Detavernier C
  • Since their early discovery, bimetallic nanoparticles have revolutionized various fields, including nanomagnetism and optics as well as heterogeneous catalysis. Knowledge buildup in the past decades has witnessed that the nanoparticle size and composition strongly impact the nanoparticle's properties and performance. Yet, conventional synthesis strategies lack proper control over the nanoparticle…
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