- Simultaneous, Label-Free and High-throughput SERS Detection of Multiple Pesticides on Ag@Three-Dimensional Silica Photonic Microsphere Array. [Journal Article]J Agric Food Chem. 2023 Feb 03 [Online ahead of print]JA
- Rapid identification and quantitative simultaneous analysis for multiple pesticide in real samples based on surface-enhanced Raman spectroscopy (SERS) is still a challenge because of sample complexity, reproducibility, and stability of SERS substrate. With use of colloidal silver nanoparticles loaded three-dimensional (3D) silica photonic microspheres (SPMs) array as the analytical platform, a SE…
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- Colloidal silver against macrophage infections and biofilms of atypical mycobacteria. [Journal Article]Biometals. 2023 Feb 02 [Online ahead of print]B
- Skin and soft tissue infection (SSTI) caused by atypical mycobacteria such as Mycobacterium abscessus and Mycobacterium avium intracellulare complex (MAIC) have increased in recent years. Current therapeutic options are limited, and hence new and better therapies are urgently required. Colloidal Silver (CS) has been identified for its widespread antibacterial properties and silver-impregnated dre…
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- [Effect evaluation on different treatment methods of the gap of immediate implantation in canine posterior mandible]. [Journal Article]Shanghai Kou Qiang Yi Xue. 2022 Aug; 31(4):337-342.SK
- CONCLUSIONS: After different treatments are performed on the gap between implants and extraction sockets, Gelatamp alone or in combination with CM has no significant effect on new bone formation, BIC, BMD, BV/TV, BS/TV, Tb.Th, Tb.N and Tb.Sp around implant.
- Dispersion and Tunable Alignment of Colloidal Silver Nanowires in a Nematic Liquid Crystal for Applications in Electric-Optic Devices. [Journal Article]ACS Appl Mater Interfaces. 2023 Jan 26 [Online ahead of print]AA
- The dispersion and tunable alignment of colloidal nanomaterials is desirable for practical applications in electric-optic (E-O) devices; however, it remains challenging for large one-dimensional nanomaterials with a large aspect ratio. Here, we demonstrate a large-scale, simple, multi-microdomain, and noncontact photoalignment technology to align colloidal silver nanowires (AgNWs, length ∼4.5 μm,…
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- Development of an on-site lateral flow immune assay based on mango leaf derived colloidal silver nanoparticles for rapid detection of Staphylococcus aureus in milk. [Journal Article]
- In order to ensure food safety, screening food samples for the presence of pathogens has been categorised as a legal testing item throughout the globe. One of the most prevalent zoonotic bacteria transmitted through dairy milk is Staphylococcus aureus. Given the limitations of the conventional detection methods, in the current study we desigined a competitive lateral flow immune assay (LFIA) usin…
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- Interaction between Nanoparticles, Membranes and Proteins: A Surface Plasmon Resonance Study. [Journal Article]
- Regardless of the promising use of nanoparticles (NPs) in biomedical applications, several toxic effects have increased the concerns about the safety of these nanomaterials. Although the pathways for NPs toxicity are diverse and dependent upon many parameters such as the nature of the nanoparticle and the biochemical environment, numerous studies have provided evidence that direct contact between…
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- Efficacy of a Silver-Based Shampoo for Treatment of Canine Malassezia: A Pilot Study. [Journal Article]J Am Anim Hosp Assoc. 2023 Jan 01; 59(1):7-11.JA
- Malassezia pachydermatis is a commensal of canines associated with Malassezia dermatitis. Consensus guidelines recommend topical and/or systemic treatment, but resistance to antifungals has been reported. The objective of this pilot study was to determine the efficacy of a 0.003% colloidal silver nanoparticle-based shampoo in the treatment of canine Malassezia dermatitis. Dogs were included based…
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- Efficacy of gelatamp in controlling the postoperative sequelae following mandibular posterior teeth extraction - A split-mouth study. [Journal Article]
- CONCLUSIONS: Based on the findings of this study, gelatamp can be effectively used to reduce postoperative sequelae such as bleeding with better soft tissue healing following extractions and surgical removal of tooth.
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- Detection and Characterization of Nodularin by Using Label-Free Surface-Enhanced Spectroscopic Techniques. [Journal Article]
- Nodularin (NOD) is a potent toxin produced by Nodularia spumigena cyanobacteria. Usually, NOD co-exists with other microcystins in environmental waters, a class of cyanotoxins secreted by certain cyanobacteria species, which makes identification difficult in the case of mixed toxins. Herein we report a complete theoretical DFT-vibrational Raman characterization of NOD along with the experimental …
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- COVID-19 Therapeutics: Use, Mechanism of Action, and Toxicity (Xenobiotics). [Review]
- SARS-CoV-2 emerged in 2019 and led to the COVID-19 pandemic. Efforts to develop therapeutics against SARS-Cov-2 led to both new treatments and attempts to repurpose existing medications. Here, we provide a narrative review of the xenobiotics and alternative remedies used or proposed to treat COVID-19. Most repositioned xenobiotics have had neither the feared toxicity nor the anticipated efficacy.…
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- Generating bioactive and antiseptic interfaces with nano-silver hydroxyapatite-based coatings by pulsed electrochemical deposition for long-term efficient cervical soft tissue sealing. [Journal Article]J Mater Chem B. 2023 01 04; 11(2):345-358.JM
- Infections related to osseointegrated implants have sparked the interest in studying titanium modification for long-term effective soft tissue sealing. Constructing a silver (Ag)-hydroxyapatite (HA) coating is regarded as an effective strategy for integrating antibiosis with osteanagenesis; however, the outcome for long-term cervical soft tissue sealing in vivo is compromised. It is challenging t…
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- A Case Study of Argyria of the Nails Secondary to Colloidal Silver Ingestion. [Case Reports]
- This case report documents the rare finding of argyria limited to the nails secondary to colloidal silver ingestion. We highlight the significance of early detection of argyria secondary to colloidal silver ingestion and offer photos of the subtle changes in the nails that indicate the development of argyria. With the popularity of over-the-counter supplementation, it is important for medical pro…
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- Silver-enhanced colloidal gold dip strip immunoassay integrated with smartphone-based colorimetry for sensitive detection of cardiac marker troponin I. [Journal Article]
- Cardiac troponin I (cTnI) is a specific cardiac biomarker for diagnosis of acute myocardial infarction (AMI). A sensitive and simple point-of-care test (POCT) is still required for early detection of AMI. To address this need, we developed a dip strip assay based on sandwich immunoassay coupled with a silver enhancement system. Pre-incubation and silver enhancement were introduced to the dip stri…
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- Silver nano/microparticle toxicity in the shrimp Litopenaeus vannamei (Boone, 1931). [Journal Article]Comp Biochem Physiol C Toxicol Pharmacol. 2023 Feb; 264:109493.CB
- The effects of silver nano/microparticles (AgP) on juvenile Litopenaeus vannamei shrimp were evaluated through several responses, aiming to use it as a prophylactic and therapeutic method. Shrimps (3.19 ± 0.13 g) were exposed to clear water for 3 h with increasing concentrations of nanosilver (0; 25; 100; and 400 μg/l). After 3 h of exposure, they were transferred to water without nanosilver for …
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- Three-Dimensional Reduced Graphene Oxide Hybrid Nano-Silver Scaffolds with High Antibacterial Properties. [Journal Article]
- In recent years, hazardous wastewater treatment has been a complex and global problem. In this work, by considering the antimicrobial activity of Ag nanoparticles (AgNPs) and reduced graphene oxide (rGO), we constructed an antibacterial device (G-AgNP) with AgNPs conformably deposited onto a 3D scaffold of reduced graphene oxide in situ. The major limitation, which is difficult to recycle, of two…
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- Analytical Model for Determination of Size-Distribution of Colloidal Silver Nanoparticles from Surface Plasmon Resonance Wavelength and Dielectric Functions. [Journal Article]
- In this work it is shown that the size of silver nanoparticles in a colloidal solution can be determined only from the wavelength of the surface plasmon resonance and material and medium dielectric functions. The size dependence of dielectric functions of silver nanoparticles becomes noticeable in nanoparticles which are smaller than 30 nm in size, which is in accordance with Mie scattering theor…
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- Fitting Procedure to Reconstruct the Size Distribution and the Concentration of Silver Colloidal Nanoparticles from UV-Vis Spectra. [Journal Article]
- In this work, a complete fitting procedure of UV-Vis spectra of silver nanoparticles in colloidal solutions is reported. The fitting function, based on the Beer-Lambert law, Mie theory, and log-normal probability distribution of nanoparticles' sizes, is developed and confirmed by 33 different independent measurements. In order to validate the accuracy of the function's behavior on different spect…
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- A glimpse into the use of silver-nanoparticles as a promising treatment for burn wounds. [Letter]
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- Silver as an Antibiotic-Independent Antimicrobial: Review of Current Formulations and Clinical Relevance. [Review]Surg Infect (Larchmt). 2022 Nov; 23(9):769-780.SI
- Background: The increase of multi-drug-resistant organisms has revived the use of silver as an alternative antibiotic-independent antimicrobial. Although silver's multimodal mechanism of action provides low risk for bacterial resistance, high local and uncontrolled concentrations have shown toxicity. This has resulted in efforts to develop novel silver formulations that are safer and more predict…
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- Aggregation-aided SERS: Selective detection of arsenic by surface-enhanced Raman spectroscopy facilitated by colloid cross-linking. [Journal Article]Talanta. 2023 Feb 01; 253:123940.T
- Arsenic of natural or industrial origin often occurs in water and makes it impotable. Due to its high toxicity, very sensitive detection is required. In the present study an ultra-sensitive arsenite (As3+) sensing is reported, based on aggregation-aided surface-enhanced Raman scattering (AA-SERS) of modified silver colloids. SERS intensity of mercapto-compounds attached to the colloidal silver na…
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- Antifungal nanosuspensions with surfactants and silver for the treatment of onychomycosis. [Journal Article]Eur J Pharm Biopharm. 2022 Oct; 179:194-205.EJ
- Fungal nail infection (Onychomycosis) often requires prolonged treatment and is associated with a high risk of resistance to treatment. Here in this contribution, we introduce a novel approach to enhance penetration and antifungal activity of the antifungal drug griseofulvin (GF). Solid dispersions were prepared with hydroxypropyl methylcellulose acetate succinate (HPMCAS) and combined with surfa…
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- 3D Spectroscopic Tracking of Individual Brownian Nanoparticles during Galvanic Exchange. [Journal Article]
- Monitoring chemical reactions in solutions at the scale of individual entities is challenging: single-particle detection requires small confocal volumes, which are hardly compatible with Brownian motion, particularly when long integration times are necessary. Here, we propose a real-time (10 Hz) holography-based nm-precision 3D tracking of single moving nanoparticles. Using this localization, the…
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- Tyndall-effect-based colorimetric assay with colloidal silver nanoparticles for quantitative point-of-care detection of creatinine using a laser pointer pen and a smartphone. [Journal Article]
- Herein, this paper initially reports a new colorimetric Tyndall effect-inspired assay (TEA) for simple, low-cost, sensitive, specific, and point-of-care detection of creatinine (an important small biomolecule) by making use of silver nanoparticles (AgNPs) as model colloidal nanoprobes for visual light scattering signaling. The naked-eye TEA method adopts negatively-charged citrate-capped AgNPs (C…
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- Nanosilver inhibits the progression of pancreatic cancer by inducing a paraptosis-like mixed type of cell death. [Journal Article]Biomed Pharmacother. 2022 Sep; 153:113511.BP
- Silver has been in clinical use since ancient times and silver nanoparticles (AgNPs) have attracted attention in cancer therapy. We investigated the mechanisms by which AgNPs inhibit pancreatic ductal adenocarcinoma (PDAC). AgNPs were synthesized and 3 human PDAC and 2 nonmalignant primary cell lines were treated with AgNPs. MTT, MAPK, colony, spheroid and scratch assays, Western blotting, TEM, a…
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- Biomedical and Textile Applications of Alternanthera sessilis Leaf Extract Mediated Synthesis of Colloidal Silver Nanoparticle. [Journal Article]
- The aqueous extract of Alternanthera sessilis (As) acts as the precursors for the quick reduction of silver ions, which leads to the formation of silver nanoparticles. In the agar, well diffusion method of the Klebsiella pneumoniae shows the minimal inhibitory concentration of 12 mm against A. sessilis mediated silver nanoparticles (As-AgNPs) at 60 µg/mL concentration. Fabric treated with novel A…
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- Synthesis of Eco-Friendly Silver Nanoparticles Using Glycyrrhizin and Evaluation of Their Antibacterial Ability. [Journal Article]
- In the present study, the biosynthesis of silver nanoparticles (AgNPs) and their antibacterial activity against gram-positive and gram-negative bacteria were investigated. Glycyrrhizin (GL) was used as a reducing agent and stabilizer to rapidly prepare the AgNPs. The distinctive absorption peak at 419 nm confirmed the formation of GL-reduced AgNPs. The TEM and particle size analysis shows that th…
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- SERS-based biosensor with Raman-active external responsive element for rapid determination of adenosine monophosphate. [Journal Article]
- Phosphorylated adenosine derivatives are important biological molecules with diverse biological functions connected with the energetic balance of the cell, biosynthesis of cell components and regulation of protein activity. Measurement of these compounds provides information about the cell signalling in the body as well as the quantity of microorganisms in the environment. Surface-enhanced Raman …
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- SERS detection of anthraquinone dyes: Using solvothermal silver colloid as the substrate. [Journal Article]Spectrochim Acta A Mol Biomol Spectrosc. 2022 Dec 05; 282:121646.SA
- Anthraquinone dyes have been widely used to color textile fibers since antiquity. Identification of the dyes can help us understand the dyeing processes and when and where the textiles were produced. Herein, we present a strategy based on surface-enhanced Raman scattering (SERS) with a novel silver colloid substrate for the detection of anthraquinone dyes. Quasi-spherical silver particles with di…
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- Use of an antiseptic rinse (NanArgol) for the oral hygiene maintenance of subjects with fixed appliances: A randomized clinical trial. [Randomized Controlled Trial]Int J Dent Hyg. 2023 Feb; 21(1):219-226.IJ
- CONCLUSIONS: The use of the test solution as an adjunct to standard oral hygiene provided a significant beneficial effect in terms of oral hygiene in patients undergoing orthodontic treatment.
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