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Unbound Medicine.
(colloidal silver)
647 results
  • Colloidal silver against macrophage infections and biofilms of atypical mycobacteria. [Journal Article]
    Biometals. 2023 Feb 02 [Online ahead of print]Feizi S, Cooksley CM, … Vreugde S
  • Skin and soft tissue infection (SSTI) caused by atypical mycobacteria such as Mycobacterium abscessus and Mycobacterium avium intracellulare complex (MAIC) have increased in recent years. Current therapeutic options are limited, and hence new and better therapies are urgently required. Colloidal Silver (CS) has been identified for its widespread antibacterial properties and silver-impregnated dre…
  • Interaction between Nanoparticles, Membranes and Proteins: A Surface Plasmon Resonance Study. [Journal Article]
    Int J Mol Sci. 2022 Dec 29; 24(1)de Macedo EF, Santos NS, … Tada DB
  • Regardless of the promising use of nanoparticles (NPs) in biomedical applications, several toxic effects have increased the concerns about the safety of these nanomaterials. Although the pathways for NPs toxicity are diverse and dependent upon many parameters such as the nature of the nanoparticle and the biochemical environment, numerous studies have provided evidence that direct contact between…
  • Efficacy of a Silver-Based Shampoo for Treatment of Canine Malassezia: A Pilot Study. [Journal Article]
    J Am Anim Hosp Assoc. 2023 Jan 01; 59(1):7-11.Jones S, Bloom P
  • Malassezia pachydermatis is a commensal of canines associated with Malassezia dermatitis. Consensus guidelines recommend topical and/or systemic treatment, but resistance to antifungals has been reported. The objective of this pilot study was to determine the efficacy of a 0.003% colloidal silver nanoparticle-based shampoo in the treatment of canine Malassezia dermatitis. Dogs were included based…
  • COVID-19 Therapeutics: Use, Mechanism of Action, and Toxicity (Xenobiotics). [Review]
    J Med Toxicol. 2023 01; 19(1):26-36.Chary MA, Barbuto AF, … Burns MM
  • SARS-CoV-2 emerged in 2019 and led to the COVID-19 pandemic. Efforts to develop therapeutics against SARS-Cov-2 led to both new treatments and attempts to repurpose existing medications. Here, we provide a narrative review of the xenobiotics and alternative remedies used or proposed to treat COVID-19. Most repositioned xenobiotics have had neither the feared toxicity nor the anticipated efficacy.…
  • A Case Study of Argyria of the Nails Secondary to Colloidal Silver Ingestion. [Case Reports]
    Cureus. 2022 Oct; 14(10):e30818.Slater K, Sommariva E, Kartono F
  • This case report documents the rare finding of argyria limited to the nails secondary to colloidal silver ingestion. We highlight the significance of early detection of argyria secondary to colloidal silver ingestion and offer photos of the subtle changes in the nails that indicate the development of argyria. With the popularity of over-the-counter supplementation, it is important for medical pro…
  • Silver nano/microparticle toxicity in the shrimp Litopenaeus vannamei (Boone, 1931). [Journal Article]
    Comp Biochem Physiol C Toxicol Pharmacol. 2023 Feb; 264:109493.Buitrago SAM, Colombo GM, … Monserrat JM
  • The effects of silver nano/microparticles (AgP) on juvenile Litopenaeus vannamei shrimp were evaluated through several responses, aiming to use it as a prophylactic and therapeutic method. Shrimps (3.19 ± 0.13 g) were exposed to clear water for 3 h with increasing concentrations of nanosilver (0; 25; 100; and 400 μg/l). After 3 h of exposure, they were transferred to water without nanosilver for …
  • Silver as an Antibiotic-Independent Antimicrobial: Review of Current Formulations and Clinical Relevance. [Review]
    Surg Infect (Larchmt). 2022 Nov; 23(9):769-780.Vishwanath N, Whitaker C, … Garcia DR
  • Background: The increase of multi-drug-resistant organisms has revived the use of silver as an alternative antibiotic-independent antimicrobial. Although silver's multimodal mechanism of action provides low risk for bacterial resistance, high local and uncontrolled concentrations have shown toxicity. This has resulted in efforts to develop novel silver formulations that are safer and more predict…
  • Antifungal nanosuspensions with surfactants and silver for the treatment of onychomycosis. [Journal Article]
    Eur J Pharm Biopharm. 2022 Oct; 179:194-205.Al-Obaidi H, Petraityte I, … Zariwala MG
  • Fungal nail infection (Onychomycosis) often requires prolonged treatment and is associated with a high risk of resistance to treatment. Here in this contribution, we introduce a novel approach to enhance penetration and antifungal activity of the antifungal drug griseofulvin (GF). Solid dispersions were prepared with hydroxypropyl methylcellulose acetate succinate (HPMCAS) and combined with surfa…
  • 3D Spectroscopic Tracking of Individual Brownian Nanoparticles during Galvanic Exchange. [Journal Article]
    ACS Nano. 2022 Sep 27; 16(9):14422-14431.Nguyen MC, Berto P, … Tessier G
  • Monitoring chemical reactions in solutions at the scale of individual entities is challenging: single-particle detection requires small confocal volumes, which are hardly compatible with Brownian motion, particularly when long integration times are necessary. Here, we propose a real-time (10 Hz) holography-based nm-precision 3D tracking of single moving nanoparticles. Using this localization, the…
  • SERS detection of anthraquinone dyes: Using solvothermal silver colloid as the substrate. [Journal Article]
    Spectrochim Acta A Mol Biomol Spectrosc. 2022 Dec 05; 282:121646.Zhu J, Liu J, … She Y
  • Anthraquinone dyes have been widely used to color textile fibers since antiquity. Identification of the dyes can help us understand the dyeing processes and when and where the textiles were produced. Herein, we present a strategy based on surface-enhanced Raman scattering (SERS) with a novel silver colloid substrate for the detection of anthraquinone dyes. Quasi-spherical silver particles with di…
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