- Toxicity of colloidal silver products and their marketing claims in Finland. [Journal Article]Toxicol Rep. 2021; 8:106-113.TR
- CONCLUSIONS: The use of quackery products such as colloidal silver can be dangerous, and their use and marketing should be controlled and restricted.
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- The Antimicrobial Activities of Silver Nanoparticles Synthesized from Medicinal Mushrooms. [Journal Article]Int J Med Mushrooms. 2020; 22(9):869-883.IJ
- Crude polysaccharide extracts derived from Agaricus bisporus (A), A. brasiliensis (B), and Phellinus linteus (P) were used for the synthesis of silver nanoparticles (AgNPs, labeled AAgNP, BAgNP, PAgNP, respectively). UV and FT-IR spectra, size distribution, and zeta potential of the respective particles were recorded, and TEM and SEM-EDS characterization was done. UV-Vis spectroscopy showed maxim…
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- Comparative Analysis of Commercial Colloidal Silver Products. [Journal Article]Int J Nanomedicine. 2020; 15:10425-10434.IJ
- CONCLUSIONS: The results of this evaluation show clearly that 70% of the commercial products evaluated contain only ionic silver. Despite the evidence showing that silver nanoparticles are not present, eight of these products are promoted by the manufacturers as 'colloidal silver'. Considering the extensive scientific research showing major differences between silver ionic and silver nanoparticles in terms of mechanisms of action, efficacy and safety, it is clear that this misrepresentation impacts the consumers and must be addressed. This study serves as blueprint for a scientific protocol to be followed by manufacturers for characterizing their silver supplements.
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- Irrational beliefs differentially predict adherence to guidelines and pseudoscientific practices during the COVID-19 pandemic. [Journal Article]Appl Cogn Psychol. 2020 Dec 07 [Online ahead of print]AC
- In the coronavirus "infodemic," people are exposed to official recommendations but also to potentially dangerous pseudoscientific advice claimed to protect against COVID-19. We examined whether irrational beliefs predict adherence to COVID-19 guidelines as well as susceptibility to such misinformation. Irrational beliefs were indexed by belief in COVID-19 conspiracy theories, COVID-19 knowledge o…
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- Citrate-silver nanoparticles and their impact on some environmental beneficial fungi. [Journal Article]Saudi J Biol Sci. 2020 Dec; 27(12):3365-3375.SJ
- Colloidal suspensions of silver nanoparticles (AgNPs) with surface modified by capping with citrate ions were synthesized by chemical reduction method. Transmission and Scanning Electron Microscopy as well as darkfield Optical Microscopy provided information on the nanoparticle morphology, with fine symmetrical grains and log-normal fitted size distribution. Small Angle X-ray Scattering method al…
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- Repeated exposure of Caco-2 versus Caco-2/HT29-MTX intestinal cell models to (nano)silver in vitro: Comparison of two commercially available colloidal silver products. [Journal Article]Sci Total Environ. 2021 Feb 01; 754:142324.ST
- Colloidal silver products are sold for a wide range of disinfectant and health applications. This has increased the potential for human exposure to silver nanoparticles (AgNPs) and ions (Ag+), for which oral ingestion is considered to be a major route of exposure. Our objective was to evaluate and compare the toxicity of two commercially available colloidal silver products on two human intestinal…
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- Ag@WS2 quantum dots for Surface Enhanced Raman Spectroscopy: Enhanced charge transfer induced highly sensitive detection of thiram from honey and beverages. [Journal Article]Food Chem. 2021 May 15; 344:128570.FC
- Novel SERS substrates is urgently in demand for rapid and sensitive analysis of toxic agrochemicals from food. In this work, a monodispersed tungsten disulfide quantum dots modified silver nanosphere (Ag@WS2QD) was prepared and used as SERS substrate. Ag@WS2QD generated uniform and stable SERS signals within 2 min, displaying great promise in "mixing and reading" detection. Compared to unmodified…
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- Trace level detection of select opioids (fentanyl, hydrocodone, oxycodone, and tramadol) in suspect pharmaceutical tablets using surface-enhanced Raman scattering (SERS) with handheld devices. [Journal Article]J Forensic Sci. 2020 Nov 02 [Online ahead of print]JF
- The opioid crisis in the USA has resulted in over 702,000 overdose fatalities between 1999 and 2017 and can be attributed to over-prescription of opioids and abuse of synthetic opioids in combination with other illicit drugs. A rapid and sensitive SERS method has been developed for trace detection of opioids including fentanyl, hydrocodone, oxycodone, and tramadol in low-dosage suspect tablets us…
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- Potent antiviral effect of silver nanoparticles on SARS-CoV-2. [Journal Article]Biochem Biophys Res Commun. 2020 11 26; 533(1):195-200.BB
- The pandemic of COVID-19 is spreading unchecked due to the lack of effective antiviral measures. Silver nanoparticles (AgNP) have been studied to possess antiviral properties and are presumed to inhibit SARS-CoV-2. Due to the need for an effective agent against SARS-CoV-2, we evaluated the antiviral effect of AgNPs. We evaluated a plethora of AgNPs of different sizes and concentration and observe…
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- Migration study of organotin compounds from food packaging by surface-enhanced Raman scattering. [Journal Article]Talanta. 2020 Dec 01; 220:121408.T
- The potential of surface-enhanced Raman scattering (SERS) has been investigated for the rapid analysis of two representative organotin compounds (OTCs): dibutyltin maleate (DTM) and tributyltin chloride (TBT), after migration tests from polyvinyl chloride (PVC), as a model food packaging material in aqueous food simulant (acetic acid 3% w/v). OTCs, often used as heat stabilizers additives for PVC…
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- Facile preparation of nanoparticle based SERS substrates for trace molecule detection. [Journal Article]Phys Chem Chem Phys. 2020 Sep 30; 22(37):21139-21146.PC
- In this work, we demonstrate that a polished Si wafer surface can be converted to possess strong surface-enhanced Raman scattering (SERS) activity by spray coating of polyol synthesized colloidal silver nanoparticles (AgNPs) at as low as 1% surface coverage. The SERS activity assays of substrate surfaces prepared with different production procedures (spray and spin coating) at different surface c…
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- Hypoglycemia is not a defining feature of metabolic crisis in mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: Further evidence of specific biochemical markers which may aid diagnosis. [Case Reports]JIMD Rep. 2020 Sep; 55(1):26-31.JR
- Mitochondrial 3-hydroxy-3-methylglutaryl-CoA (HMG Co-A) synthase (mHS) deficiency is an autosomal recessive disorder of ketone body synthesis which has traditionally been associated with hypoketotic hypoglycemia, hepatomegaly and encephalopathy, presenting in early childhood following a period of fasting. We report the third case of mHS deficiency presenting in the absence of hypoglycemia, with p…
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- Ag nanoparticle ink coupled with graphene oxide cellulose paper: a flexible and tunable SERS sensing platform. [Journal Article]Opt Lett. 2020 Aug 01; 45(15):4208-4211.OL
- Surface-enhanced Raman scattering (SERS) is highly promising for ultra-sensitive detection in a series of applications. Although extensive advances have been achieved in SERS technologies, the preparation of highly efficient SERS substrates still suffers from several limitations, including complex preparation procedures, high cost, and instability for long time storage. To address these problems,…
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- Intrasocket interventions to prevent alveolar osteitis after mandibular third molar surgery: A systematic review and network meta-analysis. [Meta-Analysis]J Craniomaxillofac Surg. 2020 Sep; 48(9):902-913.JC
- A systematic review and network meta-analysis was carried out to assess the efficacy of different intrasocket interventions immediately after mandibular third molar surgery to prevent alveolar osteitis (AO). An electronic search was undertaken using EMBASE, Cochrane Library, MEDLINE/PubMed, Web of Science, Scopus, LILACS, and grey literature. We reviewed studies published up to September 2019 and…
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- Argyria, an Unexpected Case of Skin Discoloration From Colloidal Silver Salt Ingestion. [Journal Article]J Emerg Med. 2020 Aug; 59(2):e39-e41.JE
- Argyria is a rare condition characterized by gray/blue dislocation of the skin caused by chronic exposure to silver salts.
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- Epitaxial Aluminum Surface-Enhanced Raman Spectroscopy Substrates for Large-Scale 2D Material Characterization. [Journal Article]ACS Nano. 2020 Jul 28; 14(7):8838-8845.AN
- Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive technique to identify vibrational fingerprints of trace analytes. However, present SERS techniques suffer from the lack of uniform, reproducible, and stable substrates to control the plasmonic hotspots in a wide spectral range. Here, we report the promising application of epitaxial aluminum films as a scalable plasmonic platform for …
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- A Potent and Safer Anticancer and Antibacterial Taxus-Based Green Synthesized Silver Nanoparticle. [Journal Article]Int J Nanomedicine. 2020; 15:3791-3801.IJ
- CONCLUSIONS: The production of herbal-mediated silver nanoparticles may be an efficient substitution for the silver nitrate-based medicines with less side effects.
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- High-Yield Electrochemical Synthesis of Silver Nanoparticles by Enzyme-Modified Boron-Doped Diamond Electrodes. [Journal Article]Langmuir. 2020 06 09; 36(22):6089-6094.L
- We report a novel electrochemical approach for synthesizing colloidal silver in an aqueous phase by a hemoglobin-modified boron-doped diamond electrode. The resulting Ag nanoparticles are within 10 nm in size and highly monodisperse with minimal electrode deposition. We also introduce a method for measuring the yield of synthesized nanoparticles using square-wave voltammetry as an alternative to …
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- Targeted Delivery of Colloidal Silver for MCF-7 Breast Cancer Treatment. [Journal Article]Curr Drug Deliv. 2020; 17(7):613-621.CD
- CONCLUSIONS: It is observed that tumor volumes obtained in the case of Formulation-1 were moderately inhibited from days 5 to 9. However, one of the mice in the Formulation-1 group inhibited tumor volume to 1.52 cc similar to one of the mice of positive control group (Adriamycin 1.42cc).
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- In vitro intestinal toxicity of commercially available spray disinfectant products advertised to contain colloidal silver. [Journal Article]Sci Total Environ. 2020 Aug 01; 728:138611.ST
- The use of colloidal silver-containing products as dietary supplements, immune boosters and surface disinfectants has increased in recent years which has elevated the potential for human exposure to silver nanoparticles and ions. Product mislabeling and long-term use of these products may put consumers at risk for adverse health outcomes including argyria. This study assessed several physical and…
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- Fumaric acid incorporated Ag/agar-agar hybrid hydrogel: A multifunctional avenue to tackle wound healing. [Journal Article]Mater Sci Eng C Mater Biol Appl. 2020 Jun; 111:110743.MS
- Wound and its treatment is one of the major health concerns throughout the globe. Various extrinsic and intrinsic factors can influence the dynamics of healing mechanism. One such extrinsic factor is moist environment in wound healing. The advantages of optimum hydration in wound healing are enhanced autolytic debridement, angiogenesis and accelerated cell proliferation and collagen formation. Bu…
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- New Generation of Antibacterial Products Based on Colloidal Silver. [Journal Article]
- The main objective of the present paper is the green synthesis of colloidal silver by ultrasonication starting from silver nitrate and using soluble starch as the reducing agent. Soluble starch has been used during synthesis because it is a cheap and environmentally friendly reactive. Silver colloid has been characterized by physicochemical methods: UV-VIS spectroscopy, Scanning Electron Microsco…
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- Modulatory effects of Cornus sanguinea L. mediated green synthesized silver nanoparticles on oxidative stress, COX-2/NOS2 and NFkB/pNFkB expressions in experimental inflammation in Wistar rats. [Journal Article]Mater Sci Eng C Mater Biol Appl. 2020 May; 110:110709.MS
- The present study presents a green, cost efficient and easy synthesis method of silver nanoparticles (AgNPs) using an aqueous extract of Cornus sanguinea L. fruits (CS). The phytosynthesized silver nanoparticles were characterized using various analytical techniques such as UV-Vis absorption spectroscopy, which confirmed the formation of AgNPs and FTIR spectroscopy, in order to certify the role o…
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- Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. [Journal Article]
- Lyme disease is the most common vector-borne disease in the US and Europe. Although the current recommended Lyme antibiotic treatment is effective for the majority of Lyme disease patients, about 10-20% of patients continue to suffer from persisting symptoms. There have been various anecdotal reports on the use of herbal extracts for treating patients with persisting symptoms with varying degree …
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- Antibacterial activity of iron oxide, iron nitride, and tobramycin conjugated nanoparticles against Pseudomonas aeruginosa biofilms. [Journal Article]J Nanobiotechnology. 2020 Feb 18; 18(1):35.JN
- CONCLUSIONS: Positive inhibition is reported for uncapped and alginate-capped iron-oxide NPs, and the corresponding MICs are presented. We report zero susceptibility to iron-oxide NPs capped with polyethylene glycol, suggesting that the capping agent plays a major role in enabling bactericidal ability in of the nanocomposite. Our findings suggest that the alginate-coated nanocomposites investigated in this study have the potential to overcome the bacterial biofilm barrier. Magnetic field application increases the action, likely via enhanced diffusion of the iron-oxide NPs and NP-drug conjugates through mucin and alginate barriers, which are characteristic of cystic-fibrosis respiratory infections. We demonstrate that iron-oxide NPs coated with alginate, as well as alginate-coated magnetite-tobramycin conjugates inhibit P. aeruginosa growth and biofilm formation in established colonies. We have also determined that susceptibility to tobramycin decreases for longer culture times. However, susceptibility to the iron-oxide NP compounds did not demonstrate any comparable decrease with increasing culture time. These findings imply that iron-oxide NPs are promising lower-cost alternatives to silver NPs in antibacterial coatings, solutions, and drugs, as well as other applications in which microbial abolition or infestation prevention is sought.
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- Mass Spectrometric Assay of Alpha-Fetoprotein Isoforms for Accurate Serological Evaluation. [Journal Article]Anal Chem. 2020 04 07; 92(7):4807-4813.AC
- Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death, which is demanding powerful diagnosis tools. Although the traditionally used serological biomarker alpha-fetoprotein (AFP) cannot meet the requirement of accurate diagnosis, its isoform alpha-fetoprotein L3 (AFP-L3) ratio in total AFP is emerging as a highly specific alternative. The routine electrophoretic blott…
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- Green Synthesis of Biogenic Silver Nanoparticles for Efficient Catalytic Removal of Harmful Organic Dyes. [Journal Article]Nanomaterials (Basel). 2020 Jan 24; 10(2)N
- The present article reports an environmentally benign method for synthesizing silver nanoparticles using the fruit extract of Viburnum opulus L. as a source of bioactive compounds, which can act as reducing agents of the silver ions and also as stabilizing agents of the obtained nanoparticles. The catalytic ability of the synthesized silver nanoparticles (AgNPs) to remove toxic organic dyes was a…
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- Choice of the treatment method of the inflammatory process in the alveolar tooth socket [Journal Article]Wiad Lek. 2019 Oct 31; 72(10):1957-1960.WL
- CONCLUSIONS: The complex effect of drug and surgical treatment of alveolitis was studied. The combined use of colloidal silver, Traumeel® S, Polymic®, makes it possible to eliminate the inflammatory process in the alveoli faster and to reduce the period of active disease up to 2 - 3 days.
- Antibacterial Activity of Colloidal Silver against Gram-Negative and Gram-Positive Bacteria. [Journal Article]Antibiotics (Basel). 2020 Jan 19; 9(1)A
- Due to the emergence of antimicrobial resistance, new alternative therapies are needed. Silver was used to treat bacterial infections since antiquity due to its known antimicrobial properties. Here, we aimed to evaluate the in vitro activity of colloidal silver (CS) against multidrug-resistant (MDR) Gram-negative and Gram-positive bacteria. A total of 270 strains (Acinetobacter baumannii (n = 45)…
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- Salinity modulates biochemical and histopathological changes caused by silver nanoparticles in juvenile Persian sturgeon (Acipenser persicus). [Journal Article]Environ Sci Pollut Res Int. 2020 Apr; 27(10):10658-10671.ES
- The objective of this study was to evaluate the effect of salinity on the acute and sub-chronic toxicity of silver nanoparticles (AgNPs) in Persian sturgeon. This was evaluated by exposing Persian sturgeon to AgNPs in three salinities: freshwater (F: 0.4 ppt), brackish water 1 (B1: 6 ± 0.2 ppt), and brackish water 2 (B2: 12 ± 0.3 ppt) for 14 days, which was followed by analysis of alterations in …
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