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223,631 results
  • Species-specific nitrogen resorption proficiency in legumes and nonlegumes. [Journal Article]
    J Plant Res. 2020 Jul 04 [Online ahead of print]Oikawa S, Matsui Y, … Itagaki T
  • Nitrogen (N) resorption from senescing leaves enables plants to reuse N, thereby making them less dependent on current N uptake from the environment. Therefore, N resorption is important for survival and fitness, particularly for plants growing under low N supply. We studied N resorption from senescing leaves of 25 legumes and 25 nonlegumes in a temperate region of Japan to test the hypothesis th…
  • Impact of extracellular folic acid levels on oviductal gene expression. [Journal Article]
    Theriogenology. 2020 May 21; 154:161-170.García EV, Mansilla MJ, … Barrera AD
  • Folate plays a specific role as methyl donor for nucleotide synthesis and genomic methylation patterns, which in turn are important epigenetic determinants in gene expression. Previous studies have revealed the presence of folate in bovine oviductal fluid as well as the existence of a fine-tuned regulation of the gene expression of folate receptors and transporters in bovine oviduct epithelial ce…
  • Zinc oxide nanoparticles enhance expression of maspin in human breast cancer cells. [Journal Article]
    Environ Sci Pollut Res Int. 2020 Jul 04 [Online ahead of print]Khorsandi L, Farasat M
  • Toxic and apoptotic impacts of zinc oxide nanoparticle (ZNP) on different cancer cells have been reported. Maspin (a mammary serine protease inhibitor) as a tumor suppressor gene can inhibit tumor growth and metastasis. The expression of maspin is modulated by p53, Bcl-2 family genes, and estrogen receptor α (ER-α). This study aimed to assess the ZNP effects on maspin expression in MCF-7 cells (a…
  • Aging affects sex- and organ-specific trace element profiles in mice. [Journal Article]
    Aging (Albany NY). 2020 Jul 03; 12Lossow K, Kopp JF, … Kipp AP
  • A decline of immune responses and dynamic modulation of the redox status are observed during aging and are influenced by trace elements such as copper, iodine, iron, manganese, selenium, and zinc. So far, analytical studies have focused mainly on single trace elements. Therefore, we aimed to characterize age-specific profiles of several trace elements simultaneously in serum and organs of adult a…
  • Implant-safe test in patients with peri-implantitis. [Clinical Trial]
    J Biol Regul Homeost Agents. 2020 May-Jun; 34(3 Suppl. 1):147-153.DENTAL SUPPLEMENT, Mummolo S, … Marzo G
  • Matrix metalloproteases (MMPs) are a family of zinc-dependent endopeptidases, produced by numerous cell types including fibroblasts, endothelial cells, osteoblasts, macrophages, lymphocytes and neutrophils, and capable of degrading different components of the extracellular matrix (ECM), but also cytokines, receptors and factors that regulate cell motility (1). MMPs represent the main proteolytic …
  • Evaluation of antifungal activity of cinnamaldehyde against Cryptococcus neoformans var. grubii. [Journal Article]
    Folia Microbiol (Praha). 2020 Jul 02 [Online ahead of print]Neelabh , Singh K
  • Cryptococcosis is a potentially fatal fungal disease which has aggrandized with the emergence of AIDS and antifungal resistance. The currently used antifungals lack the broad-spectrum activity and result in several toxicities during long treatment regimens. Thus, the present study aims to evaluate the antifungal activity of cinnamaldehyde against Cryptococcus neoformans var. grubii, the etiologic…
  • Bufalin-induced cardiotoxicity: new findings into mechanisms. [Journal Article]
    Chin J Nat Med. 2020 Jul; 18(7):550-560.Li M, Wang XJ, … Ma J
  • Bufalin is one of the main pharmacological and toxicological components of Venenum Bufonis and many traditional Chinese medicine preparations. The cardiotoxicity clearly limits its application to patients living in countries. Hence, an investigation of its toxicological mechanism is helpful for new drug development and treatment of the related clinical adverse reactions. We investigate the cardio…
  • Relationship between oxygen consumption and neuronal activity in a defined neural circuit. [Journal Article]
    BMC Biol. 2020 Jul 03; 18(1):76.Özugur S, Kunz L, Straka H
  • CONCLUSIONS: Controlled experimental manipulations of both the O2 level as well as the neuronal activity under in vivo-like conditions allowed to quantitatively relate spike discharge magnitudes in a particular neuronal circuitry with the O2 consumption in this area. Moreover, the possibility to distinctly manipulate various functional parameters will yield more insight in the coupling between metabolic and neuronal activity. Thus, apart from providing quantitative empiric evidence for the link between physiologically relevant spontaneous spike discharge in the brain and O2-dependent metabolism, isolated amphibian preparations are promising model systems to further dissociate the O2 dynamics in relation to neuronal computations.
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