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41,429 results
  • Case 271: Metronidazole-induced Encephalopathy. [Journal Article]
    Radiology 2019; 293(2):473-479Sun Y, Overby PJ, Mehta H
  • HistoryAn 11-year-old boy taking oral antibiotics for Fusobacterium meningitis diagnosed 3 months earlier presented to the emergency department with a 1-week history of intermittent emesis, dizziness, and vertigo and a 1-day history of wobbly gait and bilateral lower extremity paresthesia without confusion. His metabolic profile was normal. Contrast material-enhanced MRI of the brain was performe…
  • Examining emotional intelligence in older adults with chronic pain: a factor analysis approach. [Journal Article]
    Aging Ment Health 2019; :1-6Condon SE, Parmelee PA, Smith DM
  • Objective: The current study explored whether the three-factor structure of an emotional intelligence measure (attention to emotions, clarity in understanding emotions, and emotion regulation) developed in a sample of college students would replicate in a sample of older adults with chronic pain. Method: Confirmatory and exploratory factor analyses were conducted to examine the factor structure …
  • Negative myoclonus associated with pregabalin. [Case Reports]
    Yeungnam Univ J Med 2018; 35(2):240-243Park KD, Kim MK, Lee SJ
  • Negative myoclonus (NM) is a jerky, shock-like involuntary movement caused by a sudden, brief interruption of muscle contraction. An 80-year-old man presented with multifocal NM and confusion. Two days before the onset of NM, he commenced the intake of pregabalin at a dose of 150 mg/day for neuropathic pain. His NM resolved completely and mental status improved gradually after the administration …
  • Definitions, methods, and applications in interpretable machine learning. [Journal Article]
    Proc Natl Acad Sci U S A 2019Murdoch WJ, Singh C, … Yu B
  • Machine-learning models have demonstrated great success in learning complex patterns that enable them to make predictions about unobserved data. In addition to using models for prediction, the ability to interpret what a model has learned is receiving an increasing amount of attention. However, this increased focus has led to considerable confusion about the notion of interpretability. In particu…
  • RNA binding activates RIG-I by releasing an autorepressed signaling domain. [Journal Article]
    Sci Adv 2019; 5(10):eaax3641Dickey TH, Song B, Pyle AM
  • The retinoic acid-inducible gene I (RIG-I) innate immune receptor is an important immunotherapeutic target, but we lack approaches for monitoring the physical basis for its activation in vitro. This gap in our understanding has led to confusion about mechanisms of RIG-I activation and difficulty discovering agonists and antagonists. We therefore created a novel fluorescence resonance energy trans…
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