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314,440 results
  • Fabrication of amphoteric lignin and its hydrophilicity/oleophilicity at oil/water interface. [Journal Article]
    J Colloid Interface Sci 2019; 561:231-243Eraghi Kazzaz A, Fatehi P
  • Amphoteric polymers have tremendous applications in colloidal systems. Despite the enormous availability of lignin, the generation of amphoteric lignin polymer has yet to be discovered. In this work, amphoteric lignin was synthesized in an industrially attractive aqueous system via integrating the advantages of grafting quaternary ammonium groups onto lignin and polymerizing lignin with sulfonate…
  • ATP Controls the Aggregation of Aβ16-22 Peptides. [Journal Article]
    J Phys Chem B 2019Pal S, Paul S
  • The oligomerization of Aβ16-22 peptide, which is the hydrophobic core region of full-length Aβ1-42, causes Alzheimer's disease (AD). This progressive neurodegenerative disease affects over 44 million people worldwide. However, very few synthesized drug molecules are available to inhibit the aggregation of Aβ. Recently, experimental studies have shown that biological ATP molecule prevents Aβ fibri…
  • Anonymity of organ donors under discussion. [Journal Article]
    G Ital Nefrol 2019; 36(6)Oliver E, Moreno G, Grinyo JM
  • The World Health Organization declares in its Guiding Principles on Human Cell, Tissue and Organ Transplantation that organizations must ensure that the personal anonymity and privacy of donors and recipients are always protected. Hence, most of the European transplantation programs forbid any form of direct contact between the family of the deceased donor and the transplant recipient. The anonym…
  • [The challenge of the peripheral Nephrological Center: an Italian story]. [Editorial]
    G Ital Nefrol 2019; 36(6)Belotti E, Polonioli D
  • In small peripheral nephrological hospitals it can sometimes be difficult to obtain an early diagnosis and to ensure a state-of-the-art treatment. In the most complex cases, in fact, patients must be transferred to the closest Nephrological Referral Center in order to recover kidney function or improve the chance of survival. Other challenges are represented by the progressive ageing of the popul…
  • Molecular basis of the interaction of cyclophilin A with alpha-synuclein. [Journal Article]
    Angew Chem Int Ed Engl 2019Favretto F, Baker J, … Zweckstetter M
  • Peptidylprolyl isomerases (PPIases) catalyze cis/trans isomerization of prolines. The PPIase CypA colocalizes with the Parkinson's disease (PD)-associated protein α -synuclein in cells and interacts with α -synuclein oligomers. Here we describe atomic insights into the molecular details of the α -synuclein/CypA interaction. NMR spectroscopy shows that CypA catalyzes isomerization of proline 128 i…
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