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1,076,983 results
  • The legacy of biogeographic history on the composition and structure of Andean forests. [Journal Article]
    Ecology. 2020 Jul 06 [Online ahead of print]González-Caro S, Duque Á, … Yepes A
  • The biogeographic origin of species may help to explain differences in average tree height and aboveground biomass (AGB) of tropical mountain forests. After the Andean uplift, small-statured trees should have been amongst the initial colonizers of the highlands (new cold environment) from the lowland tropics since these species are pre-adapted to cold conditions with narrow vessels that are relat…
  • Physical Match Performance in Sub-elite Soccer Players - Introduction of a new Index. [Journal Article]
    Int J Sports Med. 2020 Jul 06 [Online ahead of print]Reinhardt L, Schulze S, … Kurz E
  • This investigation examined the position-specific physical performance in different locomotor categories and physiological demands concurrently in official games of sub-elite players and to present a new performance index (PI). Time-motion (distance, velocity, acceleration) and heart rate data of 55 soccer players were simultaneously captured via a GPS tracking system. The relationship between ex…
  • Spectral X-ray imaging: Conditions under which propagation-based phase-contrast is beneficial. [Journal Article]
    Phys Med Biol. 2020 Jul 06 [Online ahead of print]Schaff F, Morgan KS, … Kitchen MJ
  • Energy-resolved attenuation data in spectral X-ray imaging enables material decomposition, in which the different materials inside an object can be identified and separated virtually. Material decomposition has the drawback of increased noise in the resulting material images relative to the measured images. Recently, spectral X-ray imaging was combined with propagation-based X-ray phase-contrast …
  • Spontaneous perforation of jejunal gastrointestinal stromal tumor: A case report. [Case Reports]
    Int J Surg Case Rep. 2020 Jun 27; 73:31-34.Al-Swaiti GT, Al-Qudah MH, … Al-Nizami W
  • CONCLUSIONS: Gastrointestinal stromal tumors are relatively rare and the jejunum is the least affected among other parts of the GI tract. The majority of ruptured GISTs occur spontaneously, and are located in the stomach and small bowel. Most ruptured GISTs are associated with dismal prognosis.A jejunal gastrointestinal stromal tumor can rarely present with spontaneous perforation. However, it is important to highlight this condition, as early emergency intervention constitutes the key to a good outcome.
  • The effect of chloride, sulfate and dissolved inorganic carbon on iron release from cast iron. [Journal Article]
    Water Res. 2020 Jun 16; 183:116037.Lytle DA, Tang M, … Newton JL
  • Iron corrosion in drinking water distribution systems causes water discoloration, water quality deterioration, hydraulic loss, and even pipe failures, which are usually influenced by pipe scale structure, water hydraulics, water chemistry, and other factors. This work evaluated the effects of chloride, sulfate, and dissolved inorganic carbon (DIC) on iron release from a 90-year-old cast iron pipe…
  • IcyHot analgesic topical cream limits cardiac injury in rodents. [Journal Article]
    Transl Res. 2020 Jul 03 [Online ahead of print]Wu Y, Chen AW, … Gross ER
  • Little is known whether topical analgesic creams, whose natural products enter the blood stream after application, affect myocardial infarct size. Here we tested whether topical analgesic creams can trigger remote cardioprotection and the mechanism involved. Male Sprague Dawley rats were used for an in vivo rodent model consisting of 30 minutes left anterior descending coronary artery ischemia an…
  • Distinct patterns of surround modulation in V1 and hMT. [Journal Article]
    Neuroimage. 2020 Jul 03 [Online ahead of print]Er G, Pamir Z, Boyaci H
  • Modulation of a neuron's responses by the stimuli presented outside of its classical receptive field is ubiquitous in the visual system. This "surround modulation" mechanism is believed to be critical for efficient processing and leads to many well-known perceptual effects. The details of surround modulation, however, are still not fully understood. One of the open questions is related to the dif…
  • Links between Child and Adolescent Psychiatric Disorders and Cardiovascular Risk. [Review]
    Can J Cardiol. 2020 Jul 03 [Online ahead of print]Goldstein BI, Korczak DJ
  • This narrative review, emphasizing children and adolescents, addresses the link between five psychiatric disorders and cardiovascular risk: attention deficit hyperactivity disorder (ADHD), autism spectrum disorders, anxiety disorders, depression, and bipolar disorders. The evidence regarding cardiovascular risk factors, non-invasive measures of early atherosclerosis, and cardiovascular disease pr…
  • Dual mechanisms of Ca2+ oscillations in hepatocytes. [Journal Article]
    J Theor Biol. 2020 Jul 03 [Online ahead of print]Cloete I, Bartlett PJ, … Sneyd J
  • Calcium (Ca2+) oscillations in hepatocytes control many critical cellular functions, including glucose metabolism and bile secretion. The mechanisms underlying repetitive Ca2+ oscillations and how these mechanisms regulate these oscillations is not fully understood. Recent experimental evidence has shown that both Ca2+ regulation of the inositol 1,4,5-trisphosphate (IP3) receptor and IP3 metaboli…
  • Chemogenetic Inactivation of Orbitofrontal Cortex Decreases Cue-Induced Reinstatement of Ethanol and Sucrose Seeking in Male and Female Wistar Rats. [Journal Article]
    Alcohol Clin Exp Res. 2020 Jul 06 [Online ahead of print]Hernandez JS, Binette AN, … Moorman DE
  • CONCLUSIONS: Our results are aligned with previous work indicating a selective suppressive effect of OFC inactivation on reinstatement for alcohol and other drugs of abuse. They extend these findings to demonstrate no effect on homecage consumption or FR1 seeking as well as showing an impact of sucrose reinstatement. These data indicate that OFC plays a uniquely important role when reward seeking is driven by associations between external stimuli and internal representations of reward value, both for natural and drug rewards. They further implicate the OFC as a key structure driving relapse-associated seeking and potentially contributing to alcohol use disorder and other diseases of compulsive reward seeking.
  • Mobility restrictions for the control of epidemics: When do they work? [Journal Article]
    PLoS One. 2020; 15(7):e0235731.Espinoza B, Castillo-Chavez C, Perrings C
  • CONCLUSIONS: Mobility restrictions may not be an effective policy for controlling the spread of an infectious disease if it is assessed by the overall final epidemic size. Patterns of mobility established through the independent mobility and trade decisions of people in both communities may be sufficient to contain epidemics.
  • Electrostatic and bending energies predict staggering and splaying in nonmuscle myosin II minifilaments. [Journal Article]
    PLoS Comput Biol. 2020 Jul 06; 16(7):e1007801.Kaufmann TL, Schwarz US
  • Recent experiments with super-resolution live cell microscopy revealed that nonmuscle myosin II minifilaments are much more dynamic than formerly appreciated, often showing plastic processes such as splitting, concatenation and stacking. Here we combine sequence information, electrostatics and elasticity theory to demonstrate that the parallel staggers at 14.3, 43.2 and 72 nm have a strong tenden…
  • Hydrogel Culture Surface Stiffness Modulates Mesenchymal Stromal Cell Secretome and Alters Senescence. [Journal Article]
    Tissue Eng Part A. 2020 Jul 06 [Online ahead of print]Ogle ME, Doron G, … Temenoff JS
  • Current cell culture surfaces used for the expansion and production of mesenchymal stromal cells (MSCs) are not optimized for the production of highly secretory and nonsenescent cells. In this study, we used poly (ethylene glycol) hydrogel substrates with tunable mechanical and biochemical properties to screen the effect of culture surfaces on pro-regenerative secretome by multiplex enzyme-linked…
  • Analysis of Response Data for Assessing Treatment Effects in Comparative Clinical Studies. [Journal Article]
    Ann Intern Med. 2020 Jul 07 [Online ahead of print]Huang B, Tian L, … Wei LJ
  • In comparative studies, treatment effect is often assessed using a binary outcome that indicates response to the therapy. Commonly used summary measures for response include the cumulative and current response rates at a specific time point. The current response rate is sometimes called the probability of being in response (PBIR), which regards a patient as a responder only if they have achieved …
  • Biodegradable Inorganic Upconversion Nanocrystals for In Vivo Applications. [Journal Article]
    ACS Nano. 2020 Jul 06 [Online ahead of print]Peng P, Wu N, … Hong M
  • Lanthanide-doped inorganic upconversion nanocrystals (UCNCs) are promising as fluorescent diagnostic and therapeutic agents for in vivo applications ranging from biological imaging to disease theragnostics. However, all currently available lanthanide-doped inorganic UCNCs are not biodegradable and thus cannot be harmlessly eliminated from the body of living organism during a reasonable period of …
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