- Standard Anthracycline Based Versus Docetaxel-Capecitabine in Early High Clinical and/or Genomic Risk Breast Cancer in the EORTC 10041/BIG 3-04 MINDACT Phase III Trial. [Journal Article]J Clin Oncol 2020; :JCO1901371JC
- CONCLUSIONS: Although underpowered, this second randomization in MINDACT did not show any improvement in outcome or safety with the use of DC compared with anthracycline-based chemotherapy.
- Is early initiation of infertility treatment justified in women over the age of 35 years? [Journal Article]Reprod Biomed Online 2019RB
- CONCLUSIONS: In women older than 35 years, early initiation of the infertility work-up is associated with only a modest increase in the rate of success of IVF/ICSI. In most scenarios, this advantage may compare unfavourably with the chances of natural conception during the 6-month period.
- Prospective Initiative to Reduce Mucosal Barrier Injuries and Bloodstream Infections in Patients With Hematologic Malignancy Receiving Inpatient Chemotherapy. [Journal Article]JCO Oncol Pract 2020; :JOP1900344JO
- CONCLUSIONS: To our knowledge, this is the first published report of an intervention to prevent MBI-LCBI events. Through a multidisciplinary approach and with quality improvement tools, we were able to demonstrate a significant reduction in MBI-LCBI events.
- Effectiveness and toxicity of second-line actinomycin D in patients with methotrexate-resistant postmolar low-risk gestational trophoblastic neoplasia. [Journal Article]Gynecol Oncol 2020GO
- CONCLUSIONS: While 5-day ActD and pulsed ActD achieve comparable remission rates, due to its reduced toxicity, ease of administration, and patient convenience, pulsed ActD should be the treatment of choice for MTX-resistant postmolar low-risk GTN.
- Synthesis of carbon nanotubes via chemical vapor deposition: an advanced application in the Management of Electroplating Effluent. [Journal Article]Environ Sci Pollut Res Int 2020ES
- Iron catalyst supported over magnesium oxide had been synthesized with different percentages of Fe, i.e., 0.5, 1, and 5% employing the method of impregnation. These fabricated catalysts were used to grow carbon nanotubes (CNTs) using a chemical vapor deposition (CVD) method in the CVD reactor. The 5% Fe/MgO catalyst showed the maximum growth of CNTs. The synthesized novel CNTs (5Fe-CNTs) were inv…
Iron catalyst supported over magnesium oxide had been synthesized with different percentages of Fe, i.e., 0.5, 1, and 5% employing the method of impregnation. These fabricated catalysts were used to grow carbon nanotubes (CNTs) using a chemical vapor deposition (CVD) method in the CVD reactor. The 5% Fe/MgO catalyst showed the maximum growth of CNTs. The synthesized novel CNTs (5Fe-CNTs) were investigated for their adsorption capabilities for the removal of parts per million levels of hexavalent chromium from electroplating effluent. The 5Fe-CNTs were characterized by field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Raman spectroscopy, thermogravimetric analysis (TGA), and Zeta analyzer. The 5Fe-CNTs showed remarkable adsorption capacity of 63.3 mg g-1 toward Cr(VI) in water. The effects of various operating conditions on the removal of Cr(VI) from wastewater have been evaluated. Kinetic and thermodynamic studies were performed, and it was observed that the experimental data is in best agreement with pseudo-second-order kinetics. Besides the synthesized CNTs exhibited good recyclability for adsorbing Cr(VI) as even after 3 adsorption cycles, the adsorption capacity was reduced by less than 10%.
- First Line Gemcitabine/Pazopanib in Locally Advanced and/or Metastatic Biliary Tract Carcinoma. A Hellenic Cooperative Oncology Group Phase II Study. [Journal Article]Anticancer Res 2020; 40(2):929-938AR
- CONCLUSIONS: The low response rate precludes further testing of the combination in patients with biliary tract carcinoma.
- Molecular methods for tracking residual Plasmodium falciparum transmission in a close-to-elimination setting in Zanzibar. [Journal Article]Malar J 2020; 19(1):50MJ
- CONCLUSIONS: The approach of pre-screening reactive case detection samples in pools of five was ideal for a low prevalence setting such as in Zanzibar. Performing direct PCR on filter paper punches saves substantial time and justifies the higher cost for a polymerase suitable for amplifying DNA directly from whole blood. Molecular monitoring in community samples provided a more accurate picture of infection prevalence, as it identified a potential reservoir of infection that was largely missed by RDT. The developed qPCR-based methodology for screening large sample sets represents primarily a research tool that should inform the design of malaria elimination strategies. It may also prove beneficial for diagnostic tasks in surveillance-response activities.
- Individualizing Training in Swimming: Evidence for Utilizing the Critical Speed and Critical Stroke Rate Concepts. [Journal Article]Int J Sports Physiol Perform 2020; :1-8IJ
- CONCLUSIONS: HIIT prescribed based on the CS and CSR concepts was associated with improvements in several physiological, technical, and performance parameters in highly trained swimmers while utilizing time- and resource-efficient approach. This was achieved despite a ≥25% reduction in training volume.
- The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs. [Journal Article]PLoS One 2020; 15(1):e0227781Plos
- CONCLUSIONS: Both single and repeated doses of memantine increased DF. Severe gastric arrhythmia and long-lasting low power after repeated administration might explain possible gastric dysmotility side effects in the chronic use of memantine.
New Search Next
- First annulus formation in the European anchovy; a two-stage approach for robust validation. [Journal Article]Sci Rep 2020; 10(1):1079SR
- The age determination in fast-growing short-living species, such as European anchovy (Engraulis encrasicolus), has been widely recognized as a difficult task and bias introduced by readers leads to bias in reconstructing the population age structure. In this context, it is worth to note that age structure of fish population represents key information in fishery ecology and for stock assessment mo…
The age determination in fast-growing short-living species, such as European anchovy (Engraulis encrasicolus), has been widely recognized as a difficult task and bias introduced by readers leads to bias in reconstructing the population age structure. In this context, it is worth to note that age structure of fish population represents key information in fishery ecology and for stock assessment models. The uncertainty in estimating the age of the European anchovy by otolith reading is linked to the number of false-growth increments (checks) laid down before the annulus formation. While direct validation methods (e.g. mark-recapture, rearing, radiochemical dating) are difficult to implement specially for this short living species, the use of different indirect methods, supported by a coherent statistical approach, represents a robust and easier validation tool. A statistical modeling approach has been here adopted to assess the coherence of two well-known methods, namely Edge Analysis and Marginal Increment Analysis, in order to validate the first annulus formation in European anchovy. Both methodologies in two different yearly cycles converged toward the same result, thus confirming the annulus identification for the first year class. In addition, the completion dates of the checks and the first annulus were computed in order to gain a better insight into otolith growth dynamic. According to the species spawning period, the completion date of the first annulus falls in the summer period, while the first and second checks completion dates were mostly found in summer and winter respectively. General additive models using marginal increments as dependent variable showed a significant effect of the month, highlighting the presence of only one clear minimum in July/August, as well as specific relationships with condition factor and gonadosomatic index. Modeling the otolith edge morphology, the probability to find a hyaline band displayed in both years a similar shape, characterized by a minimum in July/August and higher values between November and January. The obtained results evidenced temporally coherent patterns providing a better insight in the otolith growth dynamic as well as a more robust validation of the first annulus formation in the European anchovy.