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816 results
  • Relationship between periodontal disease and butyric acid produced by periodontopathic bacteria. [Review]
  • IRInflamm Regen 2018; 38:23
  • Shirasugi M, Nakagawa M, … Kanamura N
  • CONCLUSIONS: Butyric acid produced by periodontopathic bacteria may promote progress of the periodontal disease state. Butyric acid is known to act as an HDAC inhibitor. Thus, we believe that advanced epigenetic analysis of the effects of butyric acid on gingival fibroblasts will help elucidate the periodontal disease pathology and facilitate discovery of new targets for periodontal disease treatment.
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