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3,079 results
  • Role of Wetting Agents and Disintegrants in Development of Danazol Nanocrystalline Tablets. [Journal Article]
    Int J Pharm 2020; :119026Meruva S, Thool P, … Kumar S
  • Poor wetting and/or particle aggregation are the shortcomings of the dried nanocrystalline suspensions, which subsequently might hinder the superior dissolution performance of the nano-crystalline suspensions. The objective of this study was to evaluate the effect of wetting agents and disintegrants on the dissolution performance of dried nanocrystals of an active pharmaceutical ingredient (API) …
  • Cutaneous endometriosis. [Case Reports]
    Int J Womens Dermatol 2019; 5(5):384-386Raffi L, Suresh R, … Twigg AR
  • Cutaneous endometriosis is a disorder that primarily affects women of reproductive age. The disorder is most commonly associated with cyclical pain during menses, but it can be difficult to diagnose in the absence of these symptoms and requires biopsy testing for a definitive diagnosis. We report on a case of a 41-year-old patient undergoing hormonal therapy for infertility who presented with a p…
  • Exogenous hormones and hereditary angioedema. [Review]
    Int Immunopharmacol 2020; 78:106080Gompel A, Fain O, … Bouillet L
  • Gonadal hormones, estrogen and androgen are strongly involved in the control of the bradykinin production. Estrogen may worsen whereas androgen can be part of the long-term prophylactic treatment. In this review, we will describe the potential impact of estrogen in the pathophysiology of hereditary angioedema (HAE). Then we will review the different hormone treatments and their implication on the…
  • Immune Thrombocytopenia in Adults: Modern Approaches to Diagnosis and Treatment. [Journal Article]
    Semin Thromb Hemost 2019Al-Samkari H, Kuter DJ
  • Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder affecting approximately 1 in 20,000 people. Patients typically present with clinically benign mucocutaneous bleeding, but morbid internal bleeding can occur. Diagnosis remains clinical, possible only after ruling out other causes of thrombocytopenia through history and laboratory testing. Many adult patients do not require treatment…
  • Drug-Induced Intracranial Hypertension: A Systematic Review and Critical Assessment of Drug-Induced Causes. [Review]
    Am J Clin Dermatol 2019Tan MG, Worley B, … Beecker J
  • CONCLUSIONS: We suggest using the term 'drug-induced intracranial hypertension' (DIIH) and propose a set of diagnostic criteria for DIIH. Our review attempts to identify DIIH-associated drugs based on a strict diagnostic and drug-causality algorithm, then stratify them into appropriate risks categories. This may ultimately assist physicians in counselling patients about the risk of DIIH when prescribing medications and recognizing this uncommon yet sight-threatening condition.
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