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6,462 results
  • Immune Thrombocytopenia in Children: Consensus and Controversies. [Review]
    Indian J Pediatr 2020; 87(2):150-157Singh G, Bansal D, Wright NAM
  • Newly diagnosed immune thrombocytopenia (ITP) is a relatively common disorder of childhood that does not require an exhaustive laboratory workup for diagnosis. A history and physical exam with a review of the peripheral smear are crucial for excluding secondary causes of thrombocytopenia. Several guidelines have been published to guide physicians in the management of ITP. However, the decision fo…
  • A first case report of dapsone inducing recurrent ventricular arrhythmia. [Case Reports]
    Eur Heart J Case Rep 2019; 3(4):1-6Wong B, Saiva L, … Galvin J
  • Ventricular arrhythmias (VAs) are life-threatening arrhythmias which are associated with significant morbidity and mortality. Ventricular arrhythmias are induced by a change in the myocardial environment altering cardiomyocyte electrophysiology. The substrate for VA includes myocardial scar, electrolyte disturbances, and drugs altering cellular electrophysiology.
  • Update on the use of dapsone in dermatology. [Review]
    Int J Dermatol 2020Ghaoui N, Hanna E, … Kurban M
  • Dapsone (4,4'-diaminodiphenylsulfone) is the only remaining sulfone used in anthropoid therapeutics and is commercially available as an oral formulation, an inhaled preparation, and a 5% or 7.5% cream. Dapsone has antimicrobial effects stemming from its sulfonamide-like ability to inhibit the synthesis of dihydrofolic acid. It also has anti-inflammatory properties such as inhibiting the productio…
  • Cutaneous lupus erythematosus: A review of the literature. [Review]
    Int J Womens Dermatol 2019; 5(5):320-329Blake SC, Daniel BS
  • Knowledge with regard to the pathogenesis of lupus erythematosus has progressed rapidly over the past decade, and with it has come promising new agents for the treatment of cutaneous lupus erythematous (CLE). Classification of CLE is performed using clinical features and histopathologic findings, and is crucial for determining prognosis and choosing therapeutic options. Preventative therapy is cr…
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