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819,645 results
  • ["Status Thymolymphaticus" - a Risk of Anaesthesia?] [Journal Article]
    Anasthesiol Intensivmed Notfallmed Schmerzther 2019; 54(9):562-570Goerig M
  • The administration of narcotics such as ether and chloroform to combat pain during surgery was overshadowed from the beginning by serious, often fatal incidents. Even the use of local anaesthetics, which were praised as being less dangerous, was not as uncomplicated as had initially been hoped for and was often fatal. Investigations into the various causes of anaesthetic incidents were carried ou…
  • Notch signaling pathway regulates T cell dysfunction in septic patients. [Journal Article]
    Int Immunopharmacol 2019; 76:105907Jin B, Liang Y, … Liu GH
  • Sepsis disrupts innate and adaptive immune response, and immune disorders may also impact clinical course of sepsis. Notch signaling pathway plays a vital role in T cell modulation and differentiation. The aim of current study was to investigate the immunoregulatory function of Notch signaling pathway to T cells in patients with sepsis and septic shock. Twenty-seven sepsis patients, twenty-five s…
  • Cytomegalovirus is a tumor-associated virus: armed and dangerous. [Review]
    Curr Opin Virol 2019; 39:49-59Cobbs C
  • Human cytomegalovirus (HCMV) gene products are present in multiple human malignancies, often in specific association with tumor cells and tumor vasculature. Emerging evidence from human and mouse models of CMV infection in cancer indicate that CMV can transform epithelial cells, promote epithelial to mesenchymal transition (EMT) and mesenchymal to epithelial (MET) in tumor cells, promote tumor an…
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