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84,163 results
  • Approach and Management of Hypertension After Kidney Transplantation. [Review]
    Front Med (Lausanne). 2020; 7:229.Tantisattamo E, Molnar MZ, … Amin A
  • Hypertension is one of the most common cardiovascular co-morbidities after successful kidney transplantation. It commonly occurs in patients with other metabolic diseases, such as diabetes mellitus, hyperlipidemia, and obesity. The pathogenesis of post-transplant hypertension is complex and is a result of the interplay between immunological and non-immunological factors. Post-transplant hypertens…
  • NeuroHeal Reduces Muscle Atrophy and Modulates Associated Autophagy. [Journal Article]
    Cells. 2020 Jun 28; 9(7)Marmolejo-Martínez-Artesero S, Romeo-Guitart D, … Casas C
  • Muscle wasting is an unmet medical need which leads to a reduction of myofiber diameter and a negative impact on the functional performance of daily activities. We previously found that a new neuroprotective drug called NeuroHeal reduced muscle atrophy produced by transient denervation. Aiming to decipher whether NeuroHeal has a direct role in muscle biology, we used herein different models of mu…
  • Role of calpains in promoting desmin filaments depolymerization and muscle atrophy. [Review]
    Biochim Biophys Acta Mol Cell Res. 2020 Jun 27 [Online ahead of print]Cohen S
  • Muscle atrophy is an inevitable sequel of fasting, denervation, aging, exposure to microgravity, and many human diseases including, cancer, type-2 diabetes, and renal failure. During atrophy the destruction of the muscle's fundamental contractile machinery, the myofibrils are accelerated leading to a reduction in muscle mass, weakness, frailty, and physical disability. Recent findings indicate th…
  • [Lower urinary tract urodynamics after reconstruction of the pelvic part of the ureter]. [Journal Article]
    Urologiia. 2020 JunKomyakov BK, Ochelenko VA, … Shevnin MV
  • CONCLUSIONS: Deformation, denervation and devascularization of detrusor are the main causes of bladder dysfunction after flap operations. Ileal ureter substitution with isoperistaltic position of the graft provides physiological passage urine from the kidney to the bladder, following good bladder function. The inclusion of antiperistaltic ileal loop in the urinary tract negatively affects the urodynamics.
  • Muscle type from which satellite cells are derived plays a role in their damage response. [Journal Article]
    Chin J Physiol. 2020 May-Jun; 63(3):113-121.Lin CY, Hou CY, … Chang H
  • The aim of this study was to evaluate the response of satellite cells to muscular atrophies which possess different pathological characteristics and which were induced by distinct damages. Right lower limbs of rats were exposed to denervation or disuse and later its tibialis anterior (TA) or soleus (SOL) muscles were analyzed. After confirming their functional impairments indicated by common but …
  • Acute abducens nerve palsy in a patient with the novel coronavirus disease (COVID-19). [Case Reports]
    J AAPOS. 2020 Jun 24 [Online ahead of print]Falcone MM, Rong AJ, … Cavuoto KM
  • We present a case of an abducens nerve palsy in a previously healthy young man in the setting of SARS-CoV-2 infection. Magnetic resonance imaging obtained 5 weeks after the onset of diplopia demonstrated an atrophic left lateral rectus muscle, which was hyperintense on T2 weighting, consistent with denervation. Although the mechanism of the nerve palsy remains unclear, it is suspected to be relat…
  • Innervation of the acromioclavicular joint by the suprascapular nerve. [Journal Article]
    Shoulder Elbow. 2020 Jun; 12(3):178-183.Borbas P, Eid K, … Feigl G
  • The suprascapular nerve is largely responsible for the majority of the sensory innervation of the acromioclavicular joint. In this anatomical study, we describe, in detail, the anatomy of the sensory innervation of the acromioclavicular joint by the branches of the suprascapular nerve.
  • Contemporary and Future Concepts on Hypertension in African Americans: COVID-19 and Beyond. [Review]
    J Natl Med Assoc. 2020 Jun 17 [Online ahead of print]Ferdinand K, Batieste T, Fleurestil M
  • CONCLUSIONS: The disparities in outcomes, which are largely attributable to a greater prevalence of comorbidities such as hypertension and obesity, in addition to adverse environmental and socioeconomic factors, highlight the necessity of specialized clinical approaches and programs for African Americans to address longstanding barriers to equitable care.
  • Opa1 Overexpression Protects from Early-Onset Mpv17-/--Related Mouse Kidney Disease. [Journal Article]
    Mol Ther. 2020 Jun 12 [Online ahead of print]Luna-Sanchez M, Benincá C, … Viscomi C
  • Moderate overexpression of Opa1, the master regulator of mitochondrial cristae morphology, significantly improved mitochondrial damage induced by drugs, surgical denervation, or oxidative phosphorylation (OXPHOS) defects due to specific impairment of a single mitochondrial respiratory chain complex. Here, we investigated the effectiveness of this approach in the Mpv17-/- mouse, characterized by p…
  • MRI appearance of jogger's foot. [Journal Article]
    Skeletal Radiol. 2020 Jun 18 [Online ahead of print]Collins MS, Tiegs-Heiden CA, Frick MA
  • CONCLUSIONS: Abnormal thickness and T2 hyperintensity of the medial plantar nerve centered at the master knot of Henry are characteristic MRI findings in patients with jogger's foot when compared with control subjects. Muscular denervation changes may also be seen, most commonly in the flexor hallucis brevis muscle.
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