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17,921 results
  • Targeting LncDACH1 promotes cardiac repair and regeneration after myocardium infarction. [Journal Article]
    Cell Death Differ 2020Cai B, Ma W, … Yang B
  • Neonatal mammalian heart maintains a transient regeneration capacity after birth, whereas this regeneration ability gradually loses in the postnatal heart. Thus, the reactivation of cardiomyocyte proliferation is emerging as a key strategy for inducing heart regeneration in adults. We have reported that a highly conserved long noncoding RNA (lncRNA) LncDACH1 was overexpressed in the failing heart…
  • Endoplasmic Reticulum Stress Contributes to Indomethacin-Induced Glioma Apoptosis. [Journal Article]
    Int J Mol Sci 2020; 21(2)Chang CY, Li JR, … Chen CJ
  • The dormancy of cellular apoptotic machinery has been highlighted as a crucial factor in therapeutic resistance, recurrence, and poor prognosis in patients with malignancy, such as malignant glioma. Increasing evidence indicates that nonsteroidal anti-inflammatory drugs (NSAIDs) confer chemopreventive effects, and indomethacin has been shown to have a novel chemotherapeutic application targeting …
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