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59 results
  • Successful Use of Oral Acyclovir in Ophthalmic Molluscum Contagiosum. [Case Reports]
    Indian Dermatol Online J 2019 Jul-Aug; 10(4):456-459Mutalik SD, Rasal YD
  • Molluscum contagiosum is a common tropical contagious viral infection, involving the skin and the mucous membranes. Ophthalmic molluscum contagiosum is a relatively uncommon condition presenting as secondary follicular conjunctivitis or kerato-conjunctivitis and may present with or without obvious dermal skin lesions. Often, unsuspected and misdiagnosed by eye care providers or observed as a conc…
  • Biologic Agents In Systemic Dermatotherapy: Cutaneous And Systemic Side Effects. [Journal Article]
    Curr Drug Saf 2017Badavanis G, Pasmatzi E, … Tsambaos D
  • The recent significant breakthroughs in the understanding of the pathogenetic mechanisms of psoriasis and other immune-mediated inflammatory disorders, have led to the emergence of a wide array of biologic agents or biologics, that are especially designed to target selective intracellular or extracellular components and pathways of the dysregulated immune response. These targeted biologic agents …
  • Dendritic nanoparticles for cutaneous drug delivery--testing in human skin and reconstructed human skin. [Review]
    Curr Pharm Des 2015; 21(20):2784-800Zoschke C, Schilrreff P, … Schafer-Korting M
  • Dendritic nanoparticles have been developed with auspicious properties like high loading capacity for guest molecules, low polydispersity and tunable end groups. Demonstrating increased cellular uptake and bypassed efflux transporters, dendritic nanoparticles may offer new treatment options for therapy-resistant diseases. New core-shell architectures address the drawbacks of initial approaches. E…
  • Dermatologic therapy in geriatric patients. [Review]
    J Dtsch Dermatol Ges 2014; 12(8):653-63; quiz 664Kratzsch D, Treudler R
  • Demographic changes in our society will lead to an increasing proportion of elderly people. Age-associated multimorbidity often results in polypharmacy and elevates the risk of adverse drug reactions. Decisive alterations in pharmacokinetics and pharmacodynamics are detectable in old age, primarily a decrease in total body water, an altered ratio of muscle mass to fatty tissue, and decreased rena…
  • Utilization of biodegradable polymeric materials as delivery agents in dermatology. [Review]
    Clin Cosmet Investig Dermatol 2014; 7:23-34Rancan F, Blume-Peytavi U, Vogt A
  • Biodegradable polymeric materials are ideal carrier systems for biomedical applications. Features like controlled and sustained delivery, improved drug pharmacokinetics, reduced side effects and safe degradation make the use of these materials very attractive in a lot of medical fields, with dermatology included. A number of studies have shown that particle-based formulations can improve the skin…
  • The other end of the rainbow: infrared and skin. [Comment]
    J Invest Dermatol 2010; 130(6):1496-9Holzer AM, Athar M, Elmets CA
  • Although infrared radiation (IRR) is ubiquitous in the terrestrial milieu, its effects on human skin have until now been largely ignored. Recent studies suggest an important role for infrared A (IRA) radiation (760-1440 nm) in dermal inflammation, photoaging, and photocarcinogenesis. In this issue, Calles et al. identify and analyze the IRA-induced transcriptome in human dermal fibroblasts. Their…
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