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37 results
  • Orf Virus Infection in Humans: A Review With a Focus on Advances in Diagnosis and Treatment. [Review]
    J Drugs Dermatol 2017; 16(7):684-689Caravaglio JV, Khachemoune A
  • Ecthyma contagiosum, also called contagious pustular dermatosis, is a zoonotic disease caused by the orf virus (OrfV). As a member of the poxviridae family and parapoxvirus genus, this dermatotropic virus has developed an array of mechanisms by which to evade the host immune system in both humans and animals. The ubiquitousness of this pathogen in sheep, goats, and deer has led to the development…
  • Poxvirus-induced angiogenesis after a thermal burn. [Case Reports]
    J Dermatol 2014; 41(9):830-3Biyik Ozkaya D, Taskın B, … Onsun N
  • Orf (contagious ecthyma) is a zoonotic infection caused by a dermatotropic parapoxvirus that commonly infects sheep, goats, and oxen. Parapoxviruses are transmitted to humans through contact with an infected animal or fomites. Orf virus infections can induce ulceration, and papulonodular, pustular, or ecthymic lesions of the skin after contact with an infected animal or contaminated fomite. Rarel…
  • Modulation of NF-кB transcription factor activation by Molluscum contagiosum virus proteins. [Review]
    Postepy Hig Med Dosw (Online) 2014; 68:129-36Struzik J, Szulc-Dąbrowska L, Niemiałtowski M
  • Molluscum contagiosum virus is a human and animal dermatotropic pathogen, which causes a severe disease in immunocompromised individuals. MCV belongs to the Poxviridae family whose members exert immunomodulatory effects on the host antiviral response. Poxviruses interfere with cell signaling pathways that lead to the activation of nuclear factor кB, a pleiotropic transcription factor which is cru…
  • Pattern recognition receptors in infectious skin diseases. [Review]
    Microbes Infect 2012; 14(11):881-93de Koning HD, Simon A, … Schalkwijk J
  • During the last decade, multiple pattern recognition receptors (PRRs) have been identified. These are involved in the innate immune response against a plethora of pathogens. However, PRR functioning can also be detrimental, even during infections. This review discusses the current knowledge on PRRs that recognize dermatotropic pathogens, and potential therapeutical implications.
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