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7,831 results
  • Structure Modeling of the Norepinephrine Transporter. [Journal Article]
    Biomolecules 2020; 10(1)Góral I, Łątka K, Bajda M
  • The norepinephrine transporter (NET) is one of the monoamine transporters. Its X-ray crystal structure has not been obtained yet. Inhibitors of human NET (hNET) play a major role in the treatment of many central and peripheral nervous system diseases. In this study, we focused on the spatial structure of a NET constructed by homology modeling on Drosophila melanogaster dopamine transporter templa…
  • Norepinephrine turnover in the left ventricle of subtotally nephrectomized rats. [Journal Article]
    Physiol Res 2019; 68(Supplementum 3):S233-S242Nalos L, Švíglerová J, … Kuncová J
  • Increased activity of the sympathetic nervous system (SNS) has been proposed as a risk factor for increased cardiovascular mortality in patients with chronic kidney disease (CKD). Information on the activity of cardiac sympathetic innervation is non-homogeneous and incomplete. The aim of our study was to evaluate the tonic effect of SNS on heart rate, norepinephrine turnover and direct and indire…
  • Adsorptive removal of cationic tricyclic antidepressants using cation-exchange resin. [Journal Article]
    Environ Sci Pollut Res Int 2020Choi JW, Bediako JK, … Yun YS
  • This study aimed to select a high-performance cation-exchange resin (CER) and estimate its uptake of positively ionized tricyclic antidepressants (TCAs), i.e., amitriptyline (AMI), imipramine (IMI), clomipramine (CLO), and desipramine (DES), which are frequently used, and detected in wastewater treatment systems. For the selection of the resin, the one-point check test of AMI in distilled water w…
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