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148 results
  • StatPearls: Paraneoplastic Pemphigus [BOOK]
    StatPearls Publishing: Treasure Island (FL) Kappius Rachael H. RH Medical University of South Carolina Ufkes Nicole A. NA Medical University of South Carolina Thiers Bruce H. BH Medical University of South Carolina BOOK
  • Paraneoplastic pemphigus (PNP) is a rare, autoimmune-mediated mucocutaneous disease that is almost always associated with an underlying neoplasm. Pemphigus comprises a group of IgG-mediated autoimmune bullous diseases in which autoantibodies react with desmosomes, the cell-to-cell adhesion structures between keratinocytes, resulting in painful skin erosions and blisters. Researchers have identifi…
  • Morphofunctional status of cardio-vascular system of rats with congenital hypothyreosis. [Journal Article]
    Wiad Lek 2019; 72(2):229-233Chuhray SM, Lavrynenko VE, … Sokurenko LM
  • CONCLUSIONS: Conclusions: In young (45-day) rats with congenital hypothyroidism the direction and expressiveness of compensatory processes is to enhance the transcytosis processes. Dystrophicdestructive changes are manifested by apoptosis in some endothelial cells, decrease in the number of biosynthetic organelles, lysis and edema of their cytoplasm. In sexually mature (100-day) rats with congenital hypothyroidism destructively-dystrophic processes in the blood capillaries of the myocardium are approximately balanced with compensatory-adaptive.
  • AGEP overlap induced by hydroxychloroquine: a case report and literature review. [Case Reports]
    J Community Hosp Intern Med Perspect 2018; 8(6):360-362Mercogliano C, Khan M, … Zimmerman R
  • Acute Generalized Exanthematous Pustulosis (AGEP) is a rare drug reaction manifesting as pustular lesions with surrounding erythema following exposure. The disease is often self-limited and treatment is supportive. It may present in an atypical variant with vesicles that desquamate into erosions, which classifies the disease as an AGEP/SJS Overlap. This overlap syndrome can carry a substantial mo…
  • Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. [Journal Article]
    J Clin Invest 2017; 127(6):2378-2391Giroux V, Lento AA, … Rustgi AK
  • The esophageal lumen is lined by a stratified squamous epithelium comprised of proliferative basal cells that differentiate while migrating toward the luminal surface and eventually desquamate. Rapid epithelial renewal occurs, but the specific cell of origin that supports this high proliferative demand remains unknown. Herein, we have described a long-lived progenitor cell population in the mouse…
  • Expedient treatment of a collodion baby. [Case Reports]
    Case Rep Dermatol Med 2011; 2011:803782Chung M, Pittenger J, … Desai N
  • Only ~270 cases of collodion babies have been reported in the literature since 1892. As the name suggests, the term "collodion baby" refers to a phenotype that can be characterized by a yellow, shiny, tight parchment-like membrane stretched over the skin. Although the collodion membrane is only an evanescent condition of the newborn, neonatal complications can occur in 45% of all collodion babies…
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