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(dexmedetomidine)
5,702 results
  • Sedation selection to reduce delirium risk: Why dexmedetomidine may be a better choice. [Journal Article]
    J Am Assoc Nurse Pract 2020Mulkey MA, Everhart DE
  • In 2018, the Society of Critical Care Medicine published the Pain Agitation Delirium Immobility and Sleep Disruption guidelines that recommend protocol assessment-based pain and sedation management. Since the publication of these guidelines, multiple studies and meta-analyses have been conducted comparing sedative options in the Intensive Care Unit (ICU) setting including dexmedetomidine and prop…
  • The Application and Analytical Pathway of Dexmedetomidine in Ischemia/Reperfusion Injury. [Journal Article]
    J Anal Methods Chem 2019; 2019:7158142Tang Y, Jia C, … Wang S
  • Ischemia/reperfusion cerebral injury can cause serious damage to nerve cells. The injured organelles are cleared by autophagy eventually, which is critical for cell survival. Dexmedetomidine is neuroprotective in various ischemia/reperfusion models. Mitochondrial calcium uniporter (MCU) is the most important channel of mitochondrial Ca2+ influx into mitochondria, where Ca2+ has a potential effect…
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