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7,211 results
  • Clinically Significant Drug-Drug Interactions with Agents for Attention-Deficit/Hyperactivity Disorder. [Review]
    CNS Drugs 2019; 33(12):1201-1222Schoretsanitis G, de Leon J, … Paulzen M
  • This article provides an overview of the pharmacokinetic drug-drug interactions (DDIs) for agents prescribed for attention-deficit/hyperactivity disorder (ADHD). Polypharmacy in the treatment of patients with ADHD leads to high exposures to DDIs and possibly adverse safety outcomes. We performed a systematic search of DDI reports for ADHD agents in Embase and Medline. We also searched for agents …
  • Recent advances in therapies for eating disorders. [Review]
    F1000Res 2019; 8Davis LE, Attia E
  • Eating disorders are serious psychiatric illnesses with high rates of morbidity and mortality. Effective treatments have traditionally included behaviorally focused therapies as well as several medication strategies. Recent years have seen promising developments in these treatments, including additional support for family-based approaches for children and adolescents, new evidence for "third-wave…
  • [Treatment of eating disorders with concurrent ADHD symptoms: knowledge, knowledge gaps and clinical implications]. [Review]
    Lakartidningen 2019; 116Svedlund NE, Norring C, … von Hausswolff-Juhlin Y
  • Emerging evidence supports a prevalence overlap between ADHD and bulimia nervosa/binge eating disorder. A high degree of ADHD symptoms may have a negative impact on recovery in eating disorders with loss of control over the eating, bingeing and purging. Screening/diagnostic evaluation of ADHD in all persons with loss of control over the eating/bingeing/purging eating disorders is required. For pa…
  • Presynaptic dopamine deficit in minimally conscious state patients following traumatic brain injury. [Journal Article]
    Brain 2019; 142(7):1887-1893Fridman EA, Osborne JR, … Schiff ND
  • Dopaminergic stimulation has been proposed as a treatment strategy for post-traumatic brain injured patients in minimally conscious state based on a clinical trial using amantadine, a weak dopamine transporter blocker. However, a specific contribution of dopaminergic neuromodulation in minimally conscious state is undemonstrated. In a phase 0 clinical trial, we evaluated 13 normal volunteers and …
  • The impact of psychostimulants on sustained attention over a 24-h period. [Journal Article]
    Cognition 2019; 193:104015Whitehurst LN, Agosta S, … Mednick SC
  • The off-label use of psychostimulants is a growing trend in healthy adults with many turning to these medications to increase alertness, attentional focus, and to help them study. However, the empirical literature on the efficacy of these medications for cognitive enhancement is controversial and the longer-term impact of these drugs on health and cognitive processing has not been thoroughly exam…
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