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699,562 results
  • Bariatric surgery-induced weight loss in patients with and without type 2 diabetes mellitus. [Journal Article]
    Clin Obes 2020; :e12356Carvalho TA, Ronsoni MF, … van de Sande-Lee S
  • Surgical treatment of obesity leads to weight loss and metabolic improvement, but it is unclear if the response differs between patients with and without type 2 diabetes. Retrospective cohort study comparing weight loss and metabolic outcomes between patients with and without type 2 diabetes, matched for body mass index (BMI), gender and age, 12 months after Roux-en-Y gastric bypass. Forty-eight …
  • Evaluating a pragmatic estimate of insulin sensitivity in Latino youth with obesity. [Journal Article]
    Clin Obes 2020Peña A, Olson ML, … Shaibi GQ
  • The whole-body insulin sensitivity index (WBISI) is a widely used surrogate of insulin sensitivity estimated from glucose and insulin concentrations during an oral glucose tolerance test (OGTT). The original WBISI uses five timepoints but reduced sampling models have been proposed. These reduced models have not been applied to the paediatric population. The purpose of this study is to compare cro…
  • The Role of MKP-5 in Adipocyte-Macrophage Interactions during Obesity. [Journal Article]
    Obes Facts 2020; :1-16Lu Y, Ma J, … Jiao P
  • CONCLUSIONS: MKP-5 promotes macrophages to switch from the M1 to the M2 phenotype and is an inflammatory inhibitor involved in obesity-induced adipose tissue inflammation and PA-triggered macrophage inflammation via the P38, JNK, and ERK MAPK pathways. MKP-5 may be developed into a potential therapeutic target for obesity-related diseases, including type 2 diabetes mellitus and insulin resistance.
  • Ultrafast Toluidine Blue Staining for Rapid On-Site Evaluation of Cytological Smears. [Journal Article]
    Acta Cytol 2020; :1-3Hewer E, Schmitt AM
  • Rapid on-site evaluation (ROSE) is one of cytopathology's "unique selling propositions." The quality, speed, and ease of handling of the staining used is a critical factor for the efficacy of the ROSE procedure. Here, we describe a modification of rapid toluidine blue staining that can be performed within 25 s, provides excellent nuclear morphology, and is compatible with subsequent Papanicolaou …
  • Maternal obesity and dyslipidemia associated with gestational diabetes mellitus (GDM). [Journal Article]
    Eur J Obstet Gynecol Reprod Biol 2020; 246:67-71O'Malley EG, Reynolds CME, … Turner MJ
  • CONCLUSIONS: Our findings suggest that the epidemiological association between GDM and dyslipidemia is mediated through maternal obesity. Women with obesity alone or GDM alone did not have an elevated OR for dyslipidemia. Interventions designed to optimise maternal lipids should prioritise women with obesity and it may be preferable for these interventions to start prior to conception.
  • Fournier's gangrene mortality; A 17- year systematic review and meta-analysis. [Review]
    Int J Infect Dis 2020El-Qushayri AE, Khalaf KM, … Abdel-Daim MM
  • CONCLUSIONS: Modifications in Fournier Gangrene Severity Index (FGSI), to include comorbidities as an important prognostic tool for FG mortality, are recommended. Close monitoring of the patients, with special interest given to the main causes of mortality, is an essential element of the management process.
  • Racial disparity in cardiac surgery risk and outcome: Report from a statewide quality initiative. [Journal Article]
    Ann Thorac Surg 2020Mazzeffi M, Holmes SD, … Maryland Cardiac Surgery Quality Initiative (MCSQI)
  • CONCLUSIONS: African American cardiac surgery patients have the highest preoperative risk in Maryland. Patients appeared to receive excellent cardiac surgery care, regardless of race, as risk adjusted mortality did not differ between groups and African American patients had lower risk adjusted odds of major morbidity or mortality than white patients. Future interventions in Maryland should be aimed at reducing preoperative risk disparity in cardiac surgery patients.
  • Lung cancer surgery for patients on hemodialysis: A decade of experience at multicenter institutions. [Journal Article]
    Ann Thorac Surg 2020Yamamoto Y, Kanzaki R, … Thoracic Surgery Study Group of Osaka University (TSSGO)
  • CONCLUSIONS: Lung cancer surgery for HD patients provides favorable long-term outcomes despite higher postoperative mortality and morbidity rates. As an extended operation is significantly associated with postoperative complications, thoracic surgeons should carefully select the type of resection based on a balance between the therapeutic benefit and invasiveness in these patients.
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