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69,067 results
  • GSTΠ stimulates caveolin-1-regulated polyamine uptake via actin remodeling. [Journal Article]
    Oncotarget 2019; 10(55):5713-5723Uemura T, Tsaprailis G, Gerner EW
  • Polyamines spermidine and spermine, and their diamine precursor putrescine, are essential for normal cellular functions in both pro- and eukaryotes. Cellular polyamine levels are regulated by biosynthesis, degradation and transport. Transport of dietary and luminal bacterial polyamines in gastrointestinal (GI) tissues plays a significant role in tissue polyamine homeostasis. We have reported that…
  • Role of Aquaporin-3 in Intestinal Injury Induced by Sepsis. [Journal Article]
    Biol Pharm Bull 2019; 42(10):1641-1650Zhu Y, Wang Y, … Li Y
  • Aquaporin-3 (AQP3) is expressed in various parts of the intestine, where it regulates the proliferation and migration of intestinal epithelial cells and the transport of glycerol and hydrogen peroxide. Our study aimed to investigate the effect on the expression of AQP3 of intestinal injury in septic mice and whether oral administration of glycerol can reduce intestinal epithelial injury and barri…
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