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2,898 results
  • Lyn regulates creatine uptake in an imatinib-resistant CML cell line. [Journal Article]
    Biochim Biophys Acta Gen Subj 2019; 1864(4):129507Okumu DO, Aponte-Collazo LJ, … Graves LM
  • CONCLUSIONS: These data suggest that Lyn can affect creatine uptake through Lyn-dependent phosphorylation and regulation of the Na+/K+-ATPase pump activity.These studies identify kinase regulation of the Na+/K+-ATPase as pivotal in regulating creatine uptake and energy metabolism in cells.
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury: Antiarrhythmic Agents [BOOK]
    National Institute of Diabetes and Digestive and Kidney Diseases: Bethesda (MD)BOOK
  • The antiarrhythmics are a heterogeneous group of medications that act to decrease cardiac automaticity and slow conduction, and are used for either or both ventricular and atrial arrhythmias. The most common use of antiarrhythmics is in the treatment of atrial fibrillation or flutter, or prevention of their recurrence in patients after electrical or medical cardioversion. Use of antiarrhythmics f…
  • [Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel]. [Journal Article]
    Nihon Yakurigaku Zasshi 2019; 154(3):103-107Fujii T, Shimizu T, … Sakai H
  • Digitoxin and digoxin are plant-derived cardiac glycosides. They are Na+,K+-ATPase (sodium pump) inhibitors, and have been used clinically for treatment and prevention of heart failure and various tachycardia. On the other hand, some epidemiological studies showed that digoxin users have a lower cancer risk compared to the non-users, and that cancer patients who had been treated with digoxin face…
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