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16,076 results
  • Lowering dietary cation-anion difference increases sow blood and milk calcium concentrations. [Journal Article]
    J Anim Sci 2019; 97(7):2927-2939Guo JY, Pasquetti TJ, Kim SW
  • A study was conducted to evaluate the effects of feeding an acidogenic diet with a low dietary cation-anion difference (DCAD) on acid-base balance, blood, milk, and urine Ca concentrations of sows during lactation. A total of 30 multiparous sows (parity: 4.5 ± 2.9, Smithfield Premium Genetic, Rose Hill, NC) were allotted to 1 of 2 dietary treatments: CON (control diets were corn-soybean meal base…
  • Novel calcitriol analogue with an oxolane group: In vitro, in vivo, and in silico studies. [Journal Article]
    Arch Pharm (Weinheim) 2019; 352(5):e1800315Obiol DJ, Martínez A, … Curino AC
  • The active form of vitamin D3 , calcitriol, is a potent antiproliferative compound. However, when effective antitumor doses of calcitriol are used, hypercalcemic effects are observed, thus blocking its therapeutic application. To overcome this problem, structural analogues have been designed with the aim of retaining or even increasing the antitumor effects while decreasing its calcemic activity.…
  • Vitamin D Receptor Gene Polymorphism: An Important Predictor of Arthritis Development. [Journal Article]
    Biomed Res Int 2019; 2019:8326246Mukhtar M, Sheikh N, … Nazir S
  • Vitamin D is an anti-inflammatory molecule and has a role in prevention of arthritis development. Biologically active form 1, 25(OH)2D3 of vitamin D can only exert its action after binding its definite vitamin D receptor encoded by VDR gene. VDR gene polymorphism leads to dysfunctioning of 1, 25(OH)2D3 ultimately disease onset. The purpose of current study was to evaluate the effect of vitamin D …
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