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(disorder of written expression)
278 results
  • Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer. [Journal Article]
    Oncotarget. 2020 Jun 02; 11(22):2092-2105.Kverneland AH, Pedersen M, … Svane IM
  • Immune therapy is a promising field within oncology but has been unsuccessful in ovarian cancer (OC). Still, there is rationale and evidence supporting immune therapy in OC. We investigated the potential for adoptive cell therapy (ACT) from in vitro expanded tumor-infiltrating lymphocytes (TILs) in combination with checkpoint inhibitors (ICI) and conducted immunological testing of ex vivo expande…
  • Sex Specific Determinants in Osteoarthritis: A Systematic Review of Preclinical Studies. [Review]
    Int J Mol Sci. 2020 May 24; 21(10)Contartese D, Tschon M, … Fini M
  • Osteoarthritis (OA) is a highly prevalent joint disease that primarily affects about 10% of the world's population over 60 years old. The purpose of this study is to systematically review the preclinical studies regarding sex differences in OA, with particular attention to the molecular aspect and gene expression, but also to the histopathological aspects. Three databases (PubMed, Scopus, and Web…
  • Disorder of written expression and dysgraphia: definition, diagnosis, and management. [Review]
    Transl Pediatr. 2020 Feb; 9(Suppl 1):S46-S54.Chung PJ, Patel DR, Nizami I
  • Writing is a complex task that is vital to learning and is usually acquired in the early years of life. 'Dysgraphia' and 'specific learning disorder in written expression' are terms used to describe those individuals who, despite exposure to adequate instruction, demonstrate writing ability discordant with their cognitive level and age. Dysgraphia can present with different symptoms at different …
  • StatPearls: Learning Disability [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Dominguez Odeilis O Lincoln Medical and Mental Health Center Carugno Paola P Lincoln Hospital & Mental Health Center BOOK
  • Learning disabilities (LDs) refer to several disorders that may affect the acquisition, organization, retention, comprehension, or the use of both verbal or nonverbal information.[1] An important aspect of defining this condition is to identify its exclusions, meaning that individuals with LDs have only specific issues with learning, but they preserve an average or above-average intelligence quot…
  • Optogenetics: Background, Methodological Advances and Potential Applications for Cardiovascular Research and Medicine. [Review]
    Front Bioeng Biotechnol. 2019; 7:466.Joshi J, Rubart M, Zhu W
  • Optogenetics is an elegant approach of precisely controlling and monitoring the biological functions of a cell, group of cells, tissues, or organs with high temporal and spatial resolution by using optical system and genetic engineering technologies. The field evolved with the need to precisely control neurons and decipher neural circuity and has made great accomplishments in neuroscience. It als…
  • A review of epigenetic contributions to post-traumatic stress disorder . [Review]
    Dialogues Clin Neurosci. 2019 12; 21(4):417-428.Howie H, Rijal CM, Ressler KJ
  • Post-traumatic stress disorder (PTSD) is a syndrome which serves as a classic example of psychiatric disorders that result from the intersection of nature and nurture, or gene and environment. By definition, PTSD requires the experience of a traumatic exposure, and yet data suggest that the risk for PTSD in the aftermath of trauma also has a heritable (genetic) component. Thus, PTSD appears to re…
  • Biological Functions of HMGN Chromosomal Proteins. [Review]
    Int J Mol Sci. 2020 Jan 10; 21(2)Nanduri R, Furusawa T, Bustin M
  • Chromatin plays a key role in regulating gene expression programs necessary for the orderly progress of development and for preventing changes in cell identity that can lead to disease. The high mobility group N (HMGN) is a family of nucleosome binding proteins that preferentially binds to chromatin regulatory sites including enhancers and promoters. HMGN proteins are ubiquitously expressed in al…
  • Headliner in Physiology and Management of Childhood Asthma: Hypothalamic-Pituitary-Adrenal Axis. [Journal Article]
    Curr Pediatr Rev. 2020; 16(1):43-52.Akcan N, Bahceciler NN
  • Asthma is the most common chronic inflammatory disease of children. Inhaled corticosteroids (ICS) are the cornerstone of asthma therapy which are the most effective, commonly used treatment of persistent asthma. Mostly, studies on the relationship between asthma and cortisol have focused on side effects of treatment. Recently, asthmatic patients not treated with ICS have been reported to have an …
  • Recent advances in understanding neocortical development. [Review]
    F1000Res. 2019; 8Borrell V
  • The neocortex is the largest part of the mammalian brain and is the seat of our higher cognitive functions. This outstanding neural structure increased massively in size and complexity during evolution in a process recapitulated today during the development of extant mammals. Accordingly, defects in neocortical development commonly result in severe intellectual and social deficits. Thus, understa…
  • Th17 Cells in Helicobacter pylori Infection: a Dichotomy of Help and Harm. [Review]
    Infect Immun. 2019 11; 87(11)Dixon BREA, Hossain R, … Algood HMS
  • Helicobacter pylori is a Gram-negative bacterium that infects the gastric epithelia of its human host. Everyone who is colonized with these pathogenic bacteria can develop gastric inflammation, termed gastritis. Additionally, a small proportion of colonized people develop more adverse outcomes, including gastric ulcer disease, gastric adenocarcinoma, or gastric mucosa-associated lymphoid tissue l…
  • StatPearls: Short Term Memory Impairment [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Cascella Marco M Istituto Nazionale Tumori - IRCCS - Fondazione Pascale, Via Mariano Semmola 80100, Napoli. Italy Al Khalili Yasir Y Virginia Commonwealth University BOOK
  • Short-term memory (STM), also referred to as short-term storage, or primary or active memory indicates different systems of memory involved in the retention of pieces of information (memory chunks) for a relatively short time (usually up to 30 seconds). In contrast, long-term memory (LTM) may hold an indefinite amount of information. The difference between the two memories, however, is not just i…
  • Biomarkers for Alzheimer's Disease in Saliva: A Systematic Review. [Journal Article]
    Dis Markers. 2019; 2019:4761054.Gleerup HS, Hasselbalch SG, Simonsen AH
  • CONCLUSIONS: Aβ42 and tau seem to be worthy candidates for future salivary biomarkers for AD, but other biomarkers such as lactoferrin and selected metabolites also have potential. More studies must be carried out with larger sample sizes and a standardization of the sampling and processing method. Factors such as diurnal variation, AD patients' decreased ability of oral self-care, and salivary flowrates must be taken into consideration.
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