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120,947 results
  • Multiple Changes Underlie Allelic Divergence of CUP2 Between Saccharomyces Species. [Journal Article]
    G3 (Bethesda) 2019Li XC, Fay JC
  • Under the model of micromutationism, phenotypic divergence between species is caused by accumulation of many small-effect changes. While mapping the causal changes to single nucleotide resolution could be difficult for diverged species, genetic dissection via chimeric constructs allows us to evaluate whether a large-effect gene is composed of many small-effect nucleotide changes. In a previously …
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