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226,356 results
  • Patient-specific access planning in minimally invasive mitral valve surgery. [Journal Article]
    Med Hypotheses 2019; 136:109475Di Perna D, Castro M, … Anselmi A
  • CONCLUSIONS: Several patient-specific factors (including the orientation of the mitral valve plane and the morphology of the chest cage) may influence the performance of a MIMVR procedure, but they are not quantitatively considered in the current planning strategy. We suggest that the clinical results of MIMVR can be improved through preoperative virtual simulation and computer-assisted surgery (through determination of working port and surgical instruments insertion positioning). Further research is justified and the development of a software tool for clinical evaluation is warranted to verify the current hypothesis.
  • LinSEM: Linearizing segmentation evaluation metrics for medical images. [Journal Article]
    Med Image Anal 2019; 60:101601Li J, Udupa JK, … Torigian DA
  • Numerous algorithms are available for segmenting medical images. Empirical discrepancy metrics are commonly used in measuring the similarity or difference between segmentations by algorithms and "true" segmentations. However, one issue with the commonly used metrics is that the same metric value often represents different levels of "clinical acceptability" for different objects depending on their…
  • Sustained Release of Growth Factors from Photoactivated Platelet Rich Plasma (PRP). [Journal Article]
    Eur J Pharm Biopharm 2019Irmak G, Demirtaş TT, Gümüşderelioğlu M
  • The goal of this study is to specify the ability of polychromatic light source (PAC), providing effective wavelengths in the range of 600-1200 nm (near-infrared region, NIR), to activate human platelets in platelet-rich plasma (PRP) and to achieve sustained and controlled release of growth factors from photoactivated platelets. PRP was isolated from human blood and treated with PAC in different t…
  • Application of A KNN-based Similarity Method to Biopharmaceutical Manufacturing. [Journal Article]
    Biotechnol Prog 2019; :e2945Ren J, Zhou R, … Romero-Torres S
  • Machine learning based similarity analysis is commonly found in many artificial intelligence applications like the one utilized in e-commerce and digital marketing. In this paper, a kNN-based (k-nearest neighbors) similarity method is proposed for rapid biopharmaceutical process diagnosis and process performance monitoring. Our proposed application measures the spatial distance between batches, i…
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