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23 results
  • Concepts in human biological rhythms. [Journal Article]
    Dialogues Clin Neurosci 2003; 5(4):327-42Reinberg A, Ashkenazi I
  • Biological rhythms and their temporal organization are adaptive phenomena to periodic changes in environmental factors linked to the earth's rotation on its axis and around the sun. Experimental data from the plant and animal kingdoms have led to many models and concepts related to biological clocks that help describe and understand the mechanisms of these changes. Many of the prevailing concepts…
  • [Daily sensation of hunger, before and after phototherapy, in subjects with depression-type seasonal affective disorder]. [Journal Article]
    Clin Ter 2001 Nov-Dec; 152(6):353-62Cugini P, Passynkova NR, … Fontana S
  • CONCLUSIONS: The pre-treatment findings suggest that the SAD-DT patients are affected by hyperorexia associated with a "phase-shift" for the circadian periodicity of their HS, which is prone to the desynchronization. Such a dyschronism reinforces the hypothesis that the SAD-DT may be pathogenetically sustained by a mechanism of "phase-shift". The post-treatment findings suggest that both the hyperorexia and dyschronism of the orectic circadian rhythm are uncorrected by the phototherapy, even though the SAD-DT patients seem to have had beneficial antidepressive effects from the therapeutic intervention. The persisting dyschronism indicates that the photic stimulus is not able to completely reset the biological clock of the suprachiasmatic nuclei, at least for the phasic modulation of the HS circadian rhythm. The orexigram, thus, could be enclosed among the clinical tools in order to assess the complete efficacy of the phototherapy in SAD-DP patients.
  • Time zone change and major psychiatric morbidity: the results of a 6-year study in Jerusalem. [Journal Article]
    Compr Psychiatry 2002 Jan-Feb; 43(1):37-40Katz G, Knobler HY, … Durst R
  • Psychiatric morbidity among foreign tourists is usually connected to external factors such as unfamiliar surroundings, language problems, and special religious experiences, as well as biological factors such as dyschronism of circadian rhythms. Long-range flights through several time zones are typically followed by symptoms of jet lag such as fatigue, severe sleep schedule disturbance, impairment…
  • [Synchronization and dyschronism of human circadian rhythms]. [Review]
    Pathol Biol (Paris) 1996; 44(6):487-95Reinberg AE, Touitou Y
  • Properties of biological rhythms are presented briefly as well as the conventional model dealing with the synchronizing effects of the day/night (or Light/Dark) alternation on the suprachiasmatic nuclei (SCN) the master-clock, which is supposed to control all our rhythms. However, apart from the SCN role, a set of experimental arguments supports the existence of biological clocks in the brain cor…
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