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970 results
  • A rare case of Myrothecium species causing mycotic keratitis: Diagnosis and management. [Case Reports]
    Med Mycol Case Rep 2019; 25:53-55Rameshkumar G, Sikha M, … Lalitha P
  • We report two cases of keratitis caused by a rare fungus Myrothecium species. Clinical presentation, identification, and management were studied. Both fungi were grown from corneal scraping and identified as M. verrucaria and M. gramineum based on the microbiological techniques and DNA sequencing analysis. Both patients were treated with topical natamycin and or voriconazole/econazole. In the fir…
  • Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes. [Journal Article]
    Sci Rep 2019; 9(1):12347Elfawal MA, Savinov SN, Aroian RV
  • Soil-transmitted nematodes (STNs), namely hookworms, whipworms, and ascarids, are extremely common parasites, infecting 1-2 billion of the poorest people worldwide. Two benzimidazoles, albendazole and mebendazole, are currently used in STN mass drug administration, with many instances of low/reduced activity reported. New drugs against STNs are urgently needed. We tested various models for STN dr…
  • Design and Characterization of Chitosan Nanoformulations for the Delivery of Antifungal Agents. [Journal Article]
    Int J Mol Sci 2019; 20(15)Calvo NL, Sreekumar S, … Leonardi D
  • Among different Candida species triggering vaginal candidiasis, Candida albicans is the most predominant yeast. It is commonly treated using azole drugs such as Tioconazole (TIO) and Econazole (ECO). However, their low water solubility may affect their therapeutic efficiency. Therefore, the aim of this research was to produce a novel chitosan nanocapsule based delivery system comprising of TIO or…
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