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721 results
  • Avatrombopag for the treatment of immune thrombocytopenia and thrombocytopenia of chronic liver disease. [Review]
    J Blood Med 2019; 10:313-321Cheloff AZ, Al-Samkari H
  • Avatrombopag is an orally-administered small molecule thrombopoietin receptor agonist. It was the third thrombopoietin receptor agonist approved for the treatment of immune thrombocytopenia and the first approved to treat periprocedural thrombocytopenia in patients with chronic liver disease (thereby providing an alternative to blood transfusions for these patients). Unlike eltrombopag, avatrombo…
  • Autoimmune thrombocytopenia: Current treatment options in adults with a focus on novel drugs. [Review]
    Eur J Haematol 2019Witkowski M, Witkowska M, Robak T
  • Immune thrombocytopenia (ITP) is an autoimmune disease characterized by platelet destruction and reduced platelet production resulting in decreased platelet level and an increased risk of bleeding. Based on the immunologic mechanism of ITP, front-line standard therapy consists of corticosteroids and intravenous immunoglobulins (IVIG). If patients do not respond to the first-line treatment, or if …
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