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  • Memantine delayed N-methyl-D-aspartate -induced convulsions in neonatal rats. [Journal Article]
    Fundam Clin Pharmacol 2015; 29(1):72-8Dhir A, Chopra K
  • Memantine (1-amino-3,5-dimethyladamantane) is a moderate-affinity uncompetitive antagonist of N-methyl-d-aspartate (NMDA) receptors. In this study, we have explored the effect of memantine against N-methyl-d-aspartate (NMDA)-induced seizures in neonatal rats. Here, we evaluated various behavioral seizure abnormalities in neonatal rats (Sprague-Dawley; postnatal day 9) after an intraperitoneal adm…
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